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See also Warning section.

Promethazine is employed to prevent and treat nausea and vomiting associated to certain conditions (such as before/after surgery, motion sickness). It is also used to treat allergy symptoms such as rash, itching, and nose that is runny. It may be used to assist you feel sleepy/relaxed before and after surgery or even to assist particular narcotic pain relievers (such as meperidine) work better. It may also be used for a short time to treat a runny nose due to the cold that is common.

Promethazine is an antihistamine and works by blocking a certain normal substance (histamine) your body makes during an allergic reaction. Its other effects (such as anti-nausea, calming, pain relief) may work by affecting other substances that are naturalsuch as acetylcholine) and also by acting directly on certain parts of the brain.

Cough-and-cold products haven't been been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat symptoms that are cold children younger than 6 years unless specifically directed by the physician. Some products (such as long-acting tablets/capsules) are not advised for use in kids more youthful than 12 years. Ask your pharmacist or doctor for lots more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious adverse effects. To decrease the risk for serious adverse effects, follow all dosage carefully directions. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking fluids that are enough making use of a humidifier or saline nose drops/spray).

How to use promethazine

Read the Patient Information Leaflet if available from your pharmacist before you start taking promethazine and each time you get a refill. If you have any relevant questions, ask your medical professional or pharmacist.

Take this medication by lips with or without meals as directed by the doctor, usually 2 to 4 times daily. For motion sickness, the first dose of promethazine should be taken 30 to 60 minutes before beginning travel. For allergies, this medication may be taken once daily at bedtime to avoid being drowsy during the day. When used before surgery, promethazine may be taken the night before or just before the procedure and may be continued afterwards as directed.

If you use the liquid kind of this medication, carefully measure the dose utilizing a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage is dependant on your actual age, medical condition, and reaction to treatment. In children, the dosage might also be based on fat. Do not increase your dose or take this medication more often than directed.

Tell your physician should your condition does not improve or if it worsens.

Exactly what conditions does promethazine treat?

Unwanted Effects

Drowsiness, dizziness, constipation, blurred vision, or mouth that is dry happen. If some of these effects persist or aggravate, inform your doctor.

To relieve dry mouth, suck (sugarless) hard candy or ice chips, chew (sugarless) gum, take in water, or use a saliva replacement.

Remember your physician has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have adverse that is serious.

Tell your doctor right away when you yourself have any severe negative effects, including: fainting, sluggish heartbeat, mental/mood changes (such as hallucinations, nervousness, irritability, restlessness, confusion), unusual/uncontrolled motions (such as fixed upward stare, neck twisting, tongue movements), shaking (tremor), difficulty urinating, effortless bleeding/bruising, indications of infection (such as for example fever, persistent sore throat), severe stomach/abdominal pain, persistent nausea/vomiting, yellowing eyes/skin.

Get help that is medical away when you have any very severe side-effects, including: slow/shallow breathing, seizures.

This medication may seldom cause a really serious condition called neuroleptic malignant syndrome (NMS). Get medical help right away when you have any of the after symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, change in the level of urine.

A tremendously severe reaction that is allergic this drug is rare. However, get medical help right away if you observe any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially regarding the face/tongue/throat), serious dizziness, trouble breathing.

This is simply not a list that is complete of adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the usa -

Call your physician for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about adverse effects. You may report side effects to wellness Canada at 1-866-234-2345.

List side that is promethazine by likelihood and severity.


See also Warning section.

Before taking promethazine, tell your medical professional or pharmacist in the event that you are allergic to it; or to any other phenothiazines (such as prochlorperazine); or if you have any other allergies. This product may contain ingredients that are inactive which causes allergic reactions or other problems. Speak to your pharmacist for lots more details.

Before using this medicine, tell your doctor or pharmacist your medical history, especially of: difficulty in breathing (such as for instance asthma, chronic obstructive pulmonary disease-COPD, rest apnea), blood/immune system problems (such as bone marrow despair), high stress within the eye (glaucoma), heart disease (such as irregular heartbeat), high blood pressure, liver disease, certain brain disorders (such as neuroleptic malignant syndrome, Reye's syndrome, seizures), stomach/intestine problems (such as for instance blockage, ulcer), overactive thyroid (hyperthyroidism), difficulty urinating (for example, due to enlarged prostate).

This drug may make you dizzy or drowsy or cause vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid beverages that are alcoholic.

Before having surgery, tell your physician or dentist about all the products you use (including prescription drugs, nonprescription medications, and herbal services and products).

Promethazine may make you more sensitive to your sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.

This medicine may make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using tubs that are hot. Whenever the weather is hot, take in a complete lot of fluids and dress lightly. If you overheat, quickly look for a accepted place to cool down and rest. Get help that is medical away for those who have a fever that doesn't get away, mental/mood changes, headache, or dizziness.

Liquid products may include sugar and/or liquor. Caution is advised you to limit/avoid these substances in your diet if you have diabetes, liver disease, or any other condition that requires. Ask your pharmacist or doctor about using this product safely.

Children may be much more responsive to the side effects of this drug, especially slowed breathing (see Warning part). This medication can cause excitement in often young children instead of drowsiness. Special care should be taken when using this medication in children who have lost a complete lot of fluid (dehydration), people who have a family reputation for unexpected baby death syndrome (SIDS), and those who are difficult to awaken from sleep.

Older adults may be more painful and sensitive to your relative side aftereffects of this drug, especially drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of dropping.

During pregnancy, this medicine should be used just when demonstrably needed. Talk about the risks and advantages with your physician.

Its unknown if promethazine passes into breast milk. It may have undesirable effects on a nursing infant. Consult your medical professional before breast-feeding.

What should I understand pregnancy that is regarding medical and administering promethazine to children or the elderly?

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