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Promethazine is in a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing the actions of chemicals within your brain. Promethazine also acts being an antihistamine. It blocks the results with the naturally sourced chemical histamine inside your body.

Promethazine is utilized to deal with allergies like itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as being a sedative or sleep aid.

Promethazine isn't for usage for the signs of asthma, pneumonia, and other lower respiratory tract infections.

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Take promethazine exactly as prescribed because of your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions in your prescription label.

Your doctor may occasionally make positive changes to dose to make sure you acquire the best comes from medicines.

Promethazine may be taken with or without food or milk.

Measure liquid medicine with a marked measuring spoon or medicine cup, not using a regular table spoon. If you do not use a dose-measuring device, ask your friendly phamacist for just one.

Call your doctor in case your symptoms don't improve, or if they become worse while taking promethazine.

This medication might cause you to definitely have unusual results with certain lab tests. Tell any doctor who treats you that you will be using promethazine.

Seek emergency medical help if you think you've used an excessive amount of this medicine. Overdose symptoms can include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.


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Take it prescribed through your doctor.

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Store promethazine at room temperature from moisture, heat, and light.

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Active Ingredient: Promethazine


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Side Effects

Get emergency medical help if you might have any of these signs of a hypersensitivity: hives; lack of breath; swelling of your respective face, lips, tongue, or throat. Stop using promethazine and call your physician at the same time if you might have these serious unwanted effects:

twitching, or uncontrollable movements of the eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking), drooling, trouble swallowing, difficulties with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling as if you might pass out;

seizure (convulsions);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

hallucinations, agitation;

nausea and stomach pain, skin rash, and jaundice (yellowing from the skin or eyes);

urinating below usual you aren't at all;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color; or

slow heartbeat, weak pulse, fainting, slow breathing (breathing may stop).

Less serious promethazine unwanted effects can sometimes include:

dizziness, drowsiness, anxiety;

blurred vision, dry mouth, stuffy nose;

ringing inside your ears;

weight gain, swelling inside your hands or feet;

impotence, trouble owning an orgasm; or


This just isn't a complete set of unwanted effects yet others may occur. Tell your medical professional about any unusual or bothersome unwanted effect.


Stop using promethazine and call a medical expert at the same time if you've twitching or uncontrollable movements of one's eyes, lips, tongue, face, arms, or legs. These could be early signs and symptoms of dangerous unwanted effects. Promethazine can cause negative effects that may impair your thinking or reactions. Be careful in case you drive or do anything that requires you to definitely be awake and alert. Avoid drinking alcohol, which may increase some from the unwanted side effects of promethazine. There are many other medicines that will talk with promethazine. Tell a medical expert about all the prescription and over-the-counter medications you have. This includes vitamins, minerals, herbal products, and prescriptions given by other doctors. Do not start using a new medication without telling a medical expert. Keep a list along with you of all of the medicines you utilize and show this list to the doctor and other doctor who treats you.

Important safety information:

Promethazine really should not be presented to a kid younger than 24 months old. Promethazine can cause severe breathing problems or death in a young child younger than 2. Carefully follow your doctor's instructions when giving this medicine to a child of any age. Do not use medicines if you might have severe asthma, emphysema, or other breathing problem, or if you are allergic to promethazine or another phenothiazines including chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), thioridazine (Mellaril), or trifluoperazine (Stelazine).

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take promethazine, tell your physician if you've got:

a reputation seizures;

heart disease or blood pressure;

liver or kidney disease;

severe asthma, emphysema, chronic obstructive pulmonary disease (COPD) or other breathing problem;

sleep apnea (breathing stops while sleeping);


a stomach ulcer or digestive obstruction;

bone marrow depression;

adrenal gland tumor (pheochromocytoma);

enlarged prostate or issues with urination;

low numbers of calcium within your blood (hypocalcemia); or

if you've got ever had a serious unwanted effect when using promethazine or other phenothiazine.

FDA pregnancy category C. It isn't known whether promethazine is harmful for an baby. Tell your doctor in the event you are pregnant or prefer to become pregnant during treatment. It is just not known whether promethazine passes into breast milk or if it could possibly harm a nursing baby. Do not use medicines without telling your doctor in case you are breast-feeding a baby. Older adults could possibly be very likely to have negative effects from promethazine.

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