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Promethazine is a gaggle of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing those things of chemicals in your brain. Promethazine also acts just as one antihistamine. It blocks the results of the naturally occurring chemical histamine within your body.

Promethazine can be used to help remedy hypersensitivity including itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as a sedative or sleep aid.

Promethazine isn't to be used for treating the signs of asthma, pneumonia, or any other lower respiratory tract infections.


Take promethazine exactly as prescribed because of your doctor. Do not take it in larger amounts or more than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to successfully get the best is a result of prescription drugs.

Promethazine can be taken with or without food or milk.

Measure liquid medicine having a marked measuring spoon or medicine cup, not with a regular table spoon. If you don't have a very dose-measuring device, ask the pharmacist for starters.

Call a medical expert if your symptoms tend not to improve, or if they worsen while taking promethazine.

This medication might cause you to definitely have unusual results with certain tests. Tell any doctor who treats you that you're using promethazine.

Seek emergency medical assistance if you believe you might have used an excessive amount this medicine. Overdose symptoms may include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.


Take it as being prescribed by your doctor.


Store promethazine at room temperature away from moisture, heat, and lightweight.


Active Ingredient: Promethazine



Side Effects

Get emergency medical help if you've got some of these signs and symptoms of an allergic reaction: hives; difficulty breathing; swelling of your respective face, lips, tongue, or throat. Stop using promethazine and call your doctor at once if you've got these serious unwanted effects:

twitching, or uncontrollable movements of your respective eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking), drooling, trouble swallowing, difficulties with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling just like you might faint;

seizure (convulsions);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

hallucinations, agitation;

nausea and stomach pain, skin rash, and jaundice (yellowing with the skin or eyes);

urinating lower than usual or otherwise in any respect;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin tone; or

slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious promethazine side effects may include:

dizziness, drowsiness, anxiety;

blurred vision, dry mouth, stuffy nose;

ringing in your ears;

weight gain, swelling in your hands or feet;

impotence, trouble owning an orgasm; or


This just isn't a complete report on unwanted effects yet others may occur. Tell your physician about any unusual or bothersome side effect.


Stop using promethazine and call your physician at the same time if you might have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs and symptoms of dangerous negative effects. Promethazine could cause side effects which could impair your thinking or reactions. Be careful if you drive or do anything that will require you to definitely be awake and alert. Avoid having a drink, that may increase some of the side effects of promethazine. There are many other medicines that may interact with promethazine. Tell your physician about every one of the prescription and over-the-counter medications you employ. This includes vitamins, minerals, herbal products, and prescriptions given by other doctors. Do not use a new medication without telling your physician. Keep a list with you of every one of the medicines you utilize and show this list to the doctor or any other healthcare provider who treats you.

Important safety information:

Promethazine mustn't be directed at a kid younger than 2 years old. Promethazine might cause severe breathing problems or death in a kid younger than 2. Carefully follow your doctor's instructions when giving this medicine to a young child of any age. Do not use prescription drugs if you've got severe asthma, emphysema, and other breathing problem, or in case you are allergic to promethazine and other phenothiazines like chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), thioridazine (Mellaril), or trifluoperazine (Stelazine).

If you've certain conditions, you will need a dose adjustment or special tests to soundly use medicines. Before you take promethazine, tell your medical professional if you've:

a history of seizures;

heart disease or hypertension;

liver or kidney disease;

severe asthma, emphysema, chronic obstructive pulmonary disease (COPD) or another breathing problem;

sleep apnea (breathing stops throughout sleep);


a stomach ulcer or digestive obstruction;

bone marrow depression;

adrenal gland tumor (pheochromocytoma);

enlarged prostate or difficulty with urination;

low amounts of calcium inside your blood (hypocalcemia); or

if you might have ever were built with a serious side effect when using promethazine or any other phenothiazine.

FDA pregnancy category C. It is just not known whether promethazine is harmful to an unborn baby. Tell your doctor in case you are pregnant or want to become pregnant during treatment. It isn't known whether promethazine passes into breast milk or if it could possibly harm a nursing baby. Do not use prescription drugs without telling your doctor in the event you are breast-feeding your baby. Older adults could possibly be more prone to have unwanted side effects from promethazine.

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