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Uses

INDICATIONS

Detrol is indicated to the management of overactive bladder with signs of urge urinary incontinence, urgency, and frequency.

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INSTRUCTIONS

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Take Detrol just as prescribed through your doctor. Do not take in larger or smaller amounts and longer than recommended. Follow the directions in your prescription label.

Your doctor may occasionally improve your dose to ensure that you receive the best results.

Take Detrol with water. Do not crush, chew, break, or open a controlled-release capsule. Swallow it whole. Breaking or opening the pill could potentially cause excessive drug to be sold at once.

Store Detrol at room temperature from moisture and warmth.

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If you missed a dose - make missed dose as soon as you remember. Skip the missed dose if it is almost time for your upcoming scheduled dose. Do not take extra medicine to generate the missed dose.

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DOSAGE

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The recommended dose of Detrol Capsules is 4 mg once daily with water and swallowed whole. The dose may be lowered to 2 mg daily according to individual response and tolerability; however, limited efficacy data are for sale for Detrol 2 mg.

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For patients with mild to moderate hepatic impairment (Child-Pugh Class A or B) or severe renal impairment (CCr 10-30 mL/min), the recommended dose of Detrol is 2 mg once daily. Detrol is not appropriate for use within patients with severe hepatic impairment (Child-Pugh Class C). Patients with CCKlO mL/min weren't studied and make use of of Detrol with this population isn't recommended.

For patients who're taking drugs which might be potent inhibitors of CYP3A4 [e.g., ketoconazole, clarithromycin, ritonavir], the recommended dose of Detrol is 2 mg once daily.

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STORAGE

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Store Detrol at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and lightweight. Do not store in the bathroom. Keep Detrol out of the reach of children and from pets.

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Side Effects

Get emergency medical help for those who have some of these signs of an allergic reaction to Detrol: hives; breathlessness; swelling of your face, lips, tongue, or throat. Stop using Detrol and call your medical professional at the same time for those who have all of these serious unwanted side effects:

Less serious Detrol unwanted effects might include:

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This is just not a complete list of unwanted effects among others may occur. Call your doctor for health advice about negative effects.

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Precautions

Before taking tolterodine, tell a medical expert or pharmacist in case you are allergic with it; or when you have every other allergies. This product might have inactive ingredients, which may cause allergies and other problems. Talk to your pharmacist for additional information.

This medication shouldn't be used if you have certain medical ailments. Before employing this medicine, consult your doctor or pharmacist when you have: problems emptying your bladder (urinary retention), severe blockage of stomach/intestines (gastric retention), a specific eye condition (uncontrolled narrow-angle glaucoma).

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Before using this medication, tell a medical expert or pharmacist your history, especially of: other bladder problems (e.g., bladder outflow obstruction), stomach/intestinal disease (e.g., ulcerative colitis), slowed movement of stomach/intestines, severe constipation, controlled narrow-angle glaucoma, kidney disease, liver disease, enlarged prostate, some muscle disease (myasthenia gravis).

Tolterodine might cause a complaint that affects the center rhythm (QT prolongation). QT prolongation can infrequently bring about serious (rarely fatal) fast/irregular heartbeat as well as other symptoms (such as severe dizziness, fainting) that require immediate medical attention. The likelihood of QT prolongation could possibly be increased for those who have certain health concerns or consider other drugs that could affect the guts rhythm (see also Drug Interactions section). Before using tolterodine, tell your medical professional or pharmacist if you have any of the following conditions: certain heart related illnesses (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation inside the EKG, sudden cardiac death).

Low degrees of potassium or magnesium in the blood may also increase your probability of QT prolongation. This risk may increase the use of certain drugs (for example diuretics/"water pills") or in case you have conditions for example severe sweating, diarrhea, or vomiting. Talk to your doctor about using tolterodine safely.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or inflict activity that needs alertness or clear vision unless you are sure you can perform such activities safely. Limit booze.

This medication might cause decreased sweating. Avoid becoming overheated in summer, saunas, or during exercise or any other strenuous activities since heatstroke may occur.

Kidney function declines when you get older. This medication is slowly removed by the kidneys. Therefore, elderly people could be more responsive to this drug.

This medication ought to be used only when clearly needed in pregnancy. It is not known whether Detrol will harm an unborn baby. Tell your physician in case you are pregnant or intend to become pregnant while employing this medication. Discuss the hazards and benefits with your physician.

It is unknown if the drug passes into breast milk. Consult your physician before breast-feeding.

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