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This combination medication is employed to take care of symptoms of Parkinson's disease or symptoms that are parkinson-likesuch as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a naturally occurring substance (dopamine) into the brain. Levodopa changes into dopamine in the brain, assisting to control movement. Carbidopa prevents the breakdown of levodopa in the bloodstream so more levodopa can enter the mind. Carbidopa can additionally reduce some of levodopa's part effects such as for instance vomiting and nausea.

How to use Sinemet

Take this medication by mouth with or without meals as directed by your doctor, often three to four times a day.

Using this medication with food might help to decrease nausea. It is best to avoid a high-protein diet (it decreases the number of levodopa that the body takes in) during treatment, unless directed otherwise by your doctor. Separate your dosage with this medication by as many hours as possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your pharmacist or doctor for more details.

The dosage is situated on your condition that is medical and to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a dose that is low gradually increase your dose. Follow your physician's directions very carefully. This combination medication comes in various strengths with various amounts of carbidopa and levodopa in each tablet. Be sure you have the strength that is correct of drugs. Your doctor may also alone prescribe carbidopa to be taken with this combination.

Make use of this medicine regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Some patients may experience a "wearing-off" (worsening of symptoms) before the dose that is next due. An "on-off" effect may also take place, in which unexpected short periods of stiffness occur. If these effects occur, contact your physician for feasible dose adjustments which could help to lessen this effect.

Do not stop taking this medication without consulting your physician. Some conditions may become even worse when this drug is quickly reduced or suddenly stopped. Your dose may gradually need to be reduced. (See also adverse Effects part.)

Tell your physician when your condition doesn't enhance or if it worsens.

Side Impacts

Dizziness, lightheadedness, sickness, vomiting, loss of appetite, difficulty sleeping, unusual dreams, or headache may happen. If any of these effects persist or worsen, tell your doctor or pharmacist immediately.

This medication may cause saliva, urine, or sweat to turn a color that is dark. This effect is safe, but your clothes might be stained.

To reduce the risk of dizziness and lightheadedness, get right up slowly whenever rising from a sitting or position that is lying.

Remember that your doctor has prescribed this medicine because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have serious adverse effects.

Some individuals taking this medication have dropped asleep abruptly during their usual activities that are dailysuch as talking on the phone, driving). In some full instances, rest occurred without any feelings of drowsiness in advance. This sleep effect may occur anytime during therapy with carbidopa/levodopa even in the event you purchased this medication for a long time. Until you have discussed this effect with your doctor if you experience increased sleepiness or fall asleep during the day, do not drive or do other possibly dangerous activities. Your danger of this sleep impact is increased by using liquor or other medications that can cause you to drowsy. See also Precautions section.

Tell your doctor right away you can't control/spasms, greatly increased eye blinking/twitching, fainting, vision changes (such as blurred vision, double vision), eye pain, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds, mental/mood changes (such as agitation, hallucinations, depression, thoughts of suicide), signs of infection (such as sore throat that doesn't go away), easy bleeding/bruising, unusual tiredness, tingling of the hands/feet, unusual strong urges (such as increased gambling, increased sexual urges) if you have any serious side effects, including: new/worsening movements.

Get medical help right away if you have actually any very severe side effects, including: upper body pain.

Suddenly stopping or reducing the dose of this medicine may rarely cause a really condition that is serious neuroleptic cancerous syndrome (NMS). Get medical help straight away if you have any of the following symptoms: fever, unusual muscle tightness, serious confusion, sweating, fast/irregular heartbeat, fast breathing.

an extremely serious reaction that is allergic this drug is rare. However, get medical help right away if you notice any observeable symptoms of a critical allergic reaction, including: rash, itching/swelling (especially associated with the face/tongue/throat), severe dizziness, difficulty respiration.

This is not a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the united states -

Phone your physician for medical advice about unwanted effects. You'll report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your medical practitioner for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.


Before using this medication, tell your doctor or pharmacist if you have any other allergies if you are allergic to carbidopa or levodopa; or. This product may contain inactive ingredients, which can cause allergies or other problems. Speak with your pharmacist for more details.

Before by using this medicine, tell your doctor or pharmacist your health background, especially of: liver disease, glaucoma, respiration problems (such as for example asthma), heart disease (such as for example heart attack, irregular heartbeat), kidney infection, stomach/intestinal ulcer, mental/mood disorders (such as depression, schizophrenia), blood problems, seizures, sleep disorders.

This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit beverages that are alcoholic. See also Side Effects section.

Before having surgery, tell your doctor or dentist about all of the products you utilize (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly required. Discuss the risks and benefits with your doctor.

Levodopa passes into breast milk. It's unknown if carbidopa passes into breast milk. Consult your doctor before breast-feeding.

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