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Chloroquine is indicated for that suppressive treatment as well as for acute attacks of malaria as a result of P. vivax, P.malariae, P. ovale, and susceptible strains of P. falciparum. The drug is also indicated to the management of extraintestinal amebiasis.


Take chloroquine with meals or milk to reduce stomach upset, unless otherwise directed by your doctor.

t is essential that you just take chloroquine only as directed. Do not take much more of it, do not take it more often, and don't take on it much more time than your physician ordered. To do so may increase the potential for serious unwanted side effects.

If you adopt chloroquine to hold you against getting malaria, keep taking it for your fulltime of treatment. If you curently have malaria, you should still keep taking chloroquine to the regular of treatment even though you set out to feel better soon after days. This will help in order to increase infection completely. If you stop taking chloroquine prematurily ., your symptoms may return.

Chloroquine is most effective whenever you go on it on the regular schedule. For example, if you are to take it once weekly to stop malaria, it is best to go on the same day per week. Or if you are to take two doses each day, one dose may be taken with breakfast and also the other with the evening meal. Make sure that you just tend not to miss any doses. If you've got any queries concerning this, seek advice from your wellbeing care professional.

If you miss a dose of chloroquine, go on it at the earliest opportunity. However, when it is almost time for your forthcoming dose, skip the missed dose and return to your normal dosing schedule. Do not double doses.


The dosage of chloroquine phosphate is frequently expressed when it comes to equivalent chloroquine base. Each 500 mg tablet of ARALEN offers the same in principle as 300 mg chloroquine base. In infants and children the dosage is preferably calculated by bodyweight.

Malaria: Suppression - Adult Dose: 500 mg (= 300 mg base) on the exact same day of every week.

Pediatric Dose: The weekly suppressive dosage is 5 mg calculated as base, per kg of bodyweight, but must not exceed the adult dose no matter weight.

If circumstances permit, suppressive therapy should begin a fortnight ahead of exposure. However, failing this in grown-ups, a preliminary double (loading) dose of merely one g (= 600 mg base), or even in children 10 mg base/kg might be drawn in two divided doses, six hours apart. The suppressive therapy needs to be continued for eight weeks after leaving the endemic area.
For Treatment of Acute Attack.

Adults: An initial dose of merely one g (= 600 mg base) as well as a different 500 mg (= 300 mg base) after six to eight hours along with a single dose of 500 mg (= 300 mg base) on every one of two consecutive days. This represents an overall dose of 2.5 g chloroquine phosphate or 1.5 g base in 72 hours.

The dosage for adults of low weight and then for infants and children needs to be determined as follows:

First dose: 10 mg base per kg (but not exceeding a single dose of 600 mg base).

Second dose: (6 hours after first dose) 5 mg base per kg (although not exceeding one particular dose of 300 mg base).

Third dose: (a day after first dose) 5 mg base per kg.

Fourth dose: (36 hours after first dose) 5 mg base per kg.

For radical cure of vivax and malariae malaria concomitant therapy with the 8-aminoquinoline compound is necessary.

Extraintestinal Amebiasis: Adults,1 g (600 mg base) daily for two main days, followed by 500 mg (300 mg base) daily for about two or three weeks. Treatment is usually combined with an effective intestinal amebicide.


Store the medicine in the closed container at room temperature, far from heat, moisture, and direct light. Keep from freezing.

Keep out of your reach of youngsters.

Do not keep outdated medicine or medicine no longer needed.

Side Effects

Along featuring its needed effects, medicine could potentially cause some unwanted side effects. Although not all of these unwanted side effects may occur, should they happen they could need medical assistance. When chloroquine is utilized in short periods of time, side effects are frequently rare. However, when it is used for quite a while and/or perhaps high doses, unwanted effects may occur and could be serious.

Check with a medical expert immediately if any of the following negative effects occur:
Less common

Blurred vision
alternation in vision
eye pain
lack of vision
Black, tarry stools
blood in urine or stools
convulsions (seizures)
cough or hoarseness
feeling faint or lightheaded
fever or chills
increased muscle weakness
lower back or side pain
mood or another mental changes
painful or difficult urination
pinpoint red spots on skin
ringing or buzzing in ears or any lack of hearing
sore throat
unusual bleeding or bruising
unusual tiredness or weakness
Symptoms of overdose
increased excitability

Note: The unwanted effects within the Less Common category above could also occur or worsen as soon as you stop taking chloroquine.

Some unwanted side effects may occur that always usually do not need medical help. These side effects might go away during treatment as the body adjusts on the medicine. Also, your health care professional may be able to let you know about ways to stop or reduce a few of these side effects. Check with your quality of life care professional if any of the following unwanted side effects continue or are bothersome or if you've got questions about them:

More common

difficulty in seeing to read
itching (more common in black patients)
loss in appetite
nausea or vomiting
stomach cramps or pain
Less common
Bleaching of hair or increased hair loss
blue-black discoloration of skin, fingernails, or within mouth
skin rash

Other side effects unpublished could also occur in some patients. If you notice another effects, check with your doctor.


If you may be taking chloroquine for a long time, it is very important that your physician check you at regular visits for virtually any blood problems or muscle weakness that may be due to chloroquine. In addition, check with your physician immediately if blurred vision, difficulty in reading, or some other difference in vision occurs during or after treatment. Your doctor might want one to have the eyes checked by an ophthalmologist (eye doctor).

If your symptoms tend not to improve in just a week or whenever they become worse, check with a medical expert.

Make sure you are aware how you reply to chloroquine prior to deciding to drive, use machines, or do just about anything else that may be dangerous if you are not able to see well.

Chloroquine could cause blurred vision, difficulty in reading, or any other difference in vision. It could also cause some people to become lightheaded.

If these reactions are especially bothersome, seek advice from your doctor.

Certain medicines ought not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines might also cause interactions that occurs. Discuss with your health care professional the usage of your medicine with food, alcohol, or tobacco.

There are no adequate and well-controlled studies evaluating the protection and efficacy of chloroquine in expectant women. Usage of chloroquine during pregnancy needs to be avoided except within the suppression or treatment of malaria when within the judgment of the physician the main benefit outweighs the potential risk on the fetus.

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