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Precautions

Do NOT use Paroxetine if:

• you're allergic to any ingredient in Paroxetine
• you consider or have taken linezolid, a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort within the last 14 days
• you consider a fenfluramine derivative (eg, dexfenfluramine), nefazodone, pimozide, a serotonin norepinephrine reuptake inhibitor (SNRI) (eg, venlafaxine), another SSRI (eg, fluoxetine), sibutramine, thioridazine, or tryptophan.

Contact a medical expert or physician straight away if these apply to you.

Some medical ailments may communicate with Paroxetine. Tell your medical professional or pharmacist in case you have any medical conditions, particularly if any with the following connect with you:

• if you are pregnant, intending to become pregnant, or are breast-feeding
• if you consider any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• for those who have allergies to medicines, foods, or other substances
• if you or perhaps a member of the family includes a good bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse
• for those who have a good reputation for seizures, heart problems, liver problems, severe kidney problems, stomach or bowel bleeding, narrow-angle glaucoma, diabetes, or metabolism problems
• if you might be dehydrated, have low blood sodium levels, or are drinking alcohol
• if you'll be having electroconvulsive therapy (ECT).

Some medicines may talk with Paroxetine. Tell your medical provider if you take every other medicines, especially any from the following:

• Anorexiants (eg, phentermine), cimetidine, fenfluramine derivatives (eg, dexfenfluramine), linezolid, lithium, MAOIs (eg, phenelzine), metoclopramide, nefazodone, selegiline, serotonin 5-HT₁ receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, venlafaxine), another SSRI (eg, fluoxetine), St. John's wort, tramadol, trazodone, or tryptophan because severe side effects, for instance a reaction which could include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, or coma, may occur
• Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) as the likelihood of bleeding, including stomach bleeding, could be increased
• Diuretics (eg, furosemide, hydrochlorothiazide) because the chance of low blood sodium levels might be increased
• Antiarrhythmics (eg, flecainide, propafenone, quinidine), H₁ antagonists (eg, astemizole, terfenadine), or phenothiazines (eg, chlorpromazine, thioridazine) because severe heart related illnesses, including irregular heartbeat, may occur
• Cyproheptadine, HIV protease inhibitors (eg, ritonavir), phenobarbital, or phenytoin since they may decrease Paroxetine's effectiveness
• Aripiprazole, atomoxetine, clozapine, fluoxetine, pimozide, procyclidine, risperidone, theophylline, or tricyclic antidepressants (eg, amitriptyline) as the likelihood of their unwanted effects could be increased by Paroxetine
• Digoxin or tamoxifen because their effectiveness could be decreased by Paroxetine.

This might not be a whole listing of all interactions that will occur. Ask your medical provider if Paroxetine may talk with other medicines which you take. Check along with your health care provider before you begin, stop, or customize the dose of the medicine.

Important safety information:

• Paroxetine could cause drowsiness, dizziness, or blurred vision. These effects may be worse if you go on it with alcohol or certain medicines. Use Paroxetine with caution. Do not drive or perform other possible unsafe tasks unless you understand how you react to it.
• Do not drink alcohol while you are taking Paroxetine.
• Check together with your doctor before you use medicines that might cause drowsiness (eg, sleep aids, muscle relaxers) while you're using Paroxetine; it may well add to their effects. Ask your friendly phamacist when you have queries about which medicines could potentially cause drowsiness.
• Several weeks may pass before your symptoms improve. Do NOT take more than the recommended dose, make positive changes to dose, or use Paroxetine more than prescribed without checking with a medical expert.
• Children, teenagers, and young adults who take Paroxetine could be at increased risk for suicidal thoughts or actions. Closely watch all patients who take Paroxetine. Contact a doctor immediately if new, worsened, or sudden symptoms including depressed mood; anxious, restless, or irritable behavior; anxiety attacks; or any unusual change in mood or behavior occur. Contact the physician immediately if any signs and symptoms of suicidal thoughts or actions occur.
• If your medical professional tells you to prevent taking Paroxetine, you will need to wait for weeks before you begin to take certain other medicines (eg, MAOIs, nefazodone). Ask your medical professional when you should start to look at your new medicines after you have stopped taking Paroxetine.
• Paroxetine may rarely spark a prolonged, painful erection. This could happen even when you are not having sexual intercourse. If this just isn't treated straight away, it could possibly bring about permanent sexual problems such as impotence. Contact your doctor right away should this happen.
• Serotonin syndrome is a possibly fatal syndrome that might be due to Paroxetine. Your risk may be greater if you take Paroxetine with certain other medicines (eg, "triptans," MAOIs). Symptoms can include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; hyperhidrosis; and nausea, vomiting, or diarrhea. Contact your doctor simultaneously for those who have any one these symptoms.
• Neuroleptic malignant syndrome (NMS) is really a possibly fatal syndrome that can be a result of Paroxetine. Your risk might be greater if Paroxetine is utilized with certain other medicines called antipsychotics (eg, aripiprazole, risperidone). Symptoms might be just like serotonin syndrome and may include fever, rigid muscles, blood pressure levels changes, and mental changes. Contact your medical professional at once in case you have any of these symptoms.
• Use Paroxetine with caution inside elderly; they might be more sensitive to its effects, especially low blood sodium levels.
• Caution is advised when working with Paroxetine in children; they might be more sensitive to its effects, especially increased risk of suicidal thoughts and actions.
• Paroxetine might cause weight changes. Children and teenagers might need regular weight and growth checks when they take Paroxetine.
• Pregnancy and breast-feeding: Paroxetine could cause harm to the fetus. If you become pregnant, speak to your doctor. You will have to discuss the benefits and risks of using Paroxetine while you are pregnant. Paroxetine can be found in breast milk. If you might be or will be breast-feeding while you use Paroxetine, check along with your doctor. Discuss any possible risks in your baby.