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Precautions

Do NOT use Aciphex if:

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• you consider an HIV protease inhibitor (eg, atazanavir).

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Contact your medical professional without delay if these connect with you.

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Some medical ailments may communicate with Aciphex. Tell your medical professional or pharmacist when you have any medical ailments, especially if any with the following sign up for you:

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• if you are pregnant, intending to conceive, or are breast-feeding

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Some medicines may connect to Aciphex. Tell your doctor in case you are taking any other medicines, especially any in the following:

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• Clarithromycin or voriconazole because they may increase the probability of Aciphex's unwanted side effects

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• Anticoagulants (eg, warfarin), cyclosporine, or digoxin since the likelihood of their side effects could be increased by Aciphex

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• Azole antifungals (eg, ketoconazole), clopidogrel, HIV protease inhibitors (eg, atazanavir), or iron as their effectiveness could be decreased by Aciphex.

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This will not be a complete set of all interactions that will occur. Ask your doctor if Aciphex may interact with other medicines that you take. Check with your medical provider before starting, stop, or affect the dose of any medicine.

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Important safety information:

• Aciphex could potentially cause drowsiness or dizziness. These effects may be worse if you go on it with alcohol or certain medicines. Use Aciphex with caution. Do not drive or perform other possibly unsafe tasks unless you understand how you respond to it.

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• Contact your doctor in case you have any symptoms of a bleeding ulcer, like black, tarry stools or vomit that looks like coffee grounds, or if you go through throat pain, chest pain, severe stomach pain, or trouble swallowing.

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• Aciphex needs to be used in combination with extreme care in Asian patients; the probability of unwanted side effects might be increased of these patients.

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• Aciphex should be in combination with extreme care in youngsters younger than 12 years; safety and effectiveness during these age are not confirmed.

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• Pregnancy and breast-feeding: If you get pregnant, contact your doctor. You will need to discuss the rewards and risks of using Aciphex when you are pregnant. It is not known if Aciphex is located in breast milk. Do not feed breast while taking Aciphex.

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