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Uses

INDICATIONS

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Keppra is utilized to take care of partial onset seizures in grown-ups and children who will be no less than one month old.
It is additionally used to treat tonic-clonic seizures in grown-ups and children who're no less than 6 yrs . old, and myoclonic seizures in older adults and kids that are a minimum of 12 years.

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INSTRUCTIONS

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Take Keppra just as prescribed through your doctor. Do not take in larger or smaller amounts and longer than recommended. Follow the directions in your prescription label.

Your doctor may occasionally alter your dose to ensure that you get the best results.

Keppra is usually taken twice per day. Take the medicine at the same time each day. You may take Keppra with or without food.

Measure liquid medicine which has a special dose-measuring spoon or medicine cup, not using a regular table spoon. If you do not use a dose-measuring device, ask your pharmacist for starters.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill could cause too much of the drug to be removed at one time.

Use Keppra regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Do not stop using Keppra without first talking to your physician, in case you feel great. You may have increased seizures in case you stop using this medicine suddenly. You should use less and less when you stop the medication completely.

Seizures are often treated which has a combination of different drugs. Use all medications as directed through your doctor. Read the medication guide or patient instructions given each medication. Do not change your doses or medication schedule without your physician's advice. .

Wear a medical alert tag or carry an ID card on the grounds that you're taking Keppra. Any medical treatment provider who treats you need to understand that you take seizure medication.

To be certain Keppra isn't causing harmful effects, your kidney function ought to be tested. Visit your doctor regularly.

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If you missed a dose - go ahead and take missed dose as soon as you remember. Skip the missed dose whether it is almost time for your next scheduled dose. Do not take extra medicine to create the missed dose.

DOSAGE

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Important Administration Instructions

Keppra is offered orally with or without food. The Keppra dosing regimen is dependent upon the indication, age bracket, dosage form (tablets or oral solution), and renal function.

Prescribe the oral solution for pediatric patients with body weight ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with body weight above 20 kg.

When using the oral solution in pediatric patients, dosing is weight-based (mg per kg) utilizing a calibrated measuring device (not a household teaspoon or tablespoon).
Keppra tablets should be swallowed whole. Keppra tablets mustn't be chewed or crushed.

Pediatric Patients

Treatment ought to be initiated which has a daily dose of 14 mg/kg into two divided doses (7 mg/kg two times a day). The daily dose needs to be increased every 14 days by increments of 14 mg/kg to the recommended daily dose of 42 mg/kg (21 mg/kg two times a day). In the clinical trial, the mean daily dose was 35 mg/kg with this generation. The effectiveness of lower doses is not studied.

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Treatment ought to be initiated with a daily dose of 20 mg/kg by 50 % divided doses (10 mg/kg two tmes a day). The daily dose should be increased by 50 percent weeks by an increment of 20 mg/kg on the recommended daily dose of 50 mg/kg (25 mg/kg two tmes a day). If a patient cannot tolerate a daily dose of 50 mg/kg, the daily dose might be reduced. In the clinical study, the mean daily dose was 47 mg/kg within this generation.

Treatment ought to be initiated having a daily dose of 20 mg/kg by 50 percent divided doses (10 mg/kg twice daily). The daily dose should be increased every two weeks by increments of 20 mg/kg towards the recommended daily dose of 60 mg/kg (30 mg/kg two times a day). If a patient cannot tolerate a day-to-day dose of 60 mg/kg, the daily dose could be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.

For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment needs to be initiated having a daily dose of 500 mg given as two times a day dosing (250 mg twice a day). The daily dose should be increased every fourteen days by increments of 500 mg with a maximum recommended daily dose of 1500 mg (750 mg twice daily).

For Keppra tablet dosing in pediatric patients weighing greater than 40 kg, treatment must be initiated which has a daily dose of 1000 mg/day given as two times a day dosing (500 mg twice daily). The daily dose needs to be increased every 2 weeks by increments of 1000 mg/day to a maximum recommended daily dose of 3000 mg (1500 mg two tmes a day).

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Partial Onset Seizures
Adults 16 Years And Older

In clinical trials, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were proved to be effective. Although in most studies there was a tendency toward greater response with higher dose [see Clinical Studies], a frequent boost in response with increased dose will not be shown.

Treatment must be initiated having a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg two tmes a day). Additional dosing increments may be given (1000 mg/day additional every 14 days) to your maximum recommended daily dose of 3000 mg. Doses more than 3000 mg/day are already employed in open-label studies for periods of half a year and longer. There is no evidence that doses higher than 3000 mg/day confer additional benefit.

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Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment must be initiated using a dose of 1000 mg/day, given as twice-daily dosing (500 mg two tmes a day). Dosage needs to be increased by 1000 mg/day every 2 weeks to the recommended daily dose of 3000 mg. The effectiveness of doses below 3000 mg/day hasn't been studied.

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Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment must be initiated with a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Dosage must be increased by 1000 mg/day every 2 weeks for the recommended daily dose of 3000 mg. The effectiveness of doses lower than 3000 mg/day has not been adequately studied.


Pediatric Patients Ages 6 To < 16 Years
Treatment should be initiated using a daily dose of 20 mg/kg by 50 % divided doses (10 mg/kg two tmes a day). The daily dose needs to be increased every 14 days by increments of 20 mg/kg towards the recommended daily dose of 60 mg/kg (30 mg/kg twice daily). The effectiveness of doses less than 60 mg/kg/day is not adequately studied. Patients with bodyweight ≤ 20 kg needs to be dosed with oral solution. Patients with body mass above 20 kg might be dosed with either tablets or oral solution. Only whole tablets needs to be administered.

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Adult Patients With Impaired Renal Function
Keppra dosing have to be individualized according towards the patient's renal function status.

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STORAGE

Store Keppra at room temperature from moisture, heat, and light.

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Side Effects

Get emergency medical help in the event you have some of these signs and symptoms of a hypersensitivity to Keppra: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, like: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your medical professional at once should you use a serious complication such as:

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Less serious Keppra unwanted side effects might include:

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This is not a complete set of side effects among others may occur. Tell a medical expert about any unusual or bothersome side-effect.

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Precautions

You must avoid using Keppra in the event you are allergic to levetiracetam.

To ensure you can safely take Keppra, tell your physician in case you have kidney disease or high blood pressure levels.

You might have thoughts about suicide while investing in this medicine. Tell a medical expert if you have signs of depression or suicidal thoughts during the first a few months of treatment, or when your dose is changed.

Your family and other caregivers should also be tuned in to changes in your mood or symptoms. Your doctor should check you at regular visits.

FDA pregnancy category C. It just isn't known whether Keppra will harm an developing fetus, but creating a seizure while pregnant could harm the mother and the baby. Tell a medical expert if you are pregnant or plan to conceive while using this medication. Do not start or stop taking Keppra during pregnancy without your doctor's advice. Seizure control is critical while pregnant. The benefit of preventing seizures may outweigh any risks presented by taking Keppra. Follow a medical expert's instructions about taking Keppra if you are pregnant. Levetiracetam can pass into breast milk and could harm a nursing baby. You should not breast-feed while you're using Keppra. Do not give medicines to some child devoid of the advice of a doctor. Your child's dose needs are based on age and weight. The child should remain under the care of your doctor while applying this medicine.

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Do not stop using Keppra without first talking to your doctor, although you may feel great. You could have increased seizures should you stop using Keppra suddenly. You may need to use much less when you stop the medication completely.

You might have thoughts about suicide while taking Keppra. Your doctor will likely need to check you at regular visits. Do not miss any scheduled appointments.

Report any new or worsening symptoms to your medical professional, including: mood or behavior changes, depression, anxiety, or in case you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Wear a medical alert tag or carry an ID card praoclaiming that you adopt Keppra. Any health care bills provider who treats you have to know that you adopt seizure medication.

Keppra may impair your notions or reactions. Be careful in the event you drive or do anything that will need that you be alert. Tell your doctor in the event you are pregnant or plan to become pregnant while applying this medication. Do not start or stop taking Keppra in pregnancy without your physician's advice. Having a seizure in pregnancy could harm both mother and also the baby. Seizure control is critical during pregnancy as well as the great things about preventing seizures may outweigh any risks resulting from using Keppra.

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Avoid having a drink. It can increase many of the unwanted side effects of Keppra and may may also increase the risk of seizures. This medication may impair your notions or reactions. Be careful in case you drive or do just about anything that will require that you be alert.

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