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Uses

INDICATIONS

Keppra is employed to deal with partial onset seizures in older adults and kids that are no less than 30 days old.
It is also used to deal with tonic-clonic seizures in grown-ups and children who're no less than 6 years old, and myoclonic seizures in grown-ups and youngsters who are no less than 12 years.

INSTRUCTIONS

Take Keppra just as prescribed because of your doctor. Do not take in larger or smaller amounts or over recommended. Follow the directions on your prescription label.

Your doctor may occasionally alter your dose to successfully acquire the best results.

Keppra is generally taken twice daily. Take the medicine concurrently every day. You may take Keppra with or without food.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask the pharmacist for just one.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill might cause excessive drug to be sold previously.

Use Keppra regularly to get the most benefit. Get your prescription refilled before you run out of medication completely.

Do not stop using Keppra without first talking to a medical expert, even though you feel great. You might have increased seizures in the event you stop applying this medicine suddenly. You should use less prior to deciding to stop the medication completely.

Seizures tend to be treated with a combination of different drugs. Use all medications as directed because of your doctor. Read the medication guide or patient instructions supplied with each medication. Do not make positive changes to doses or medication schedule without your medical professional's advice. .

Wear a medical alert tag or carry an ID card proclaiming that you're taking Keppra. Any health care bills provider who treats you need to understand that you adopt seizure medication.

To be sure Keppra is just not causing harmful effects, your kidney function may need to be tested. Visit your physician regularly.

If you missed a dose - take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make in the missed dose.

DOSAGE

Important Administration Instructions

Keppra is offered orally with or without food. The Keppra dosing regimen depends upon the indication, age bracket, dosage form (tablets or oral solution), and renal function.

Prescribe the oral solution for pediatric patients with body mass ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with bodyweight above 20 kg.

When with all the oral solution in pediatric patients, dosing is weight-based (mg per kg) by using a calibrated measuring device (not just a household teaspoon or tablespoon).
Keppra tablets must be swallowed whole. Keppra tablets mustn't be chewed or crushed.

Pediatric Patients

Treatment must be initiated having a daily dose of 14 mg/kg by 50 percent divided doses (7 mg/kg two times a day). The daily dose should be increased every two weeks by increments of 14 mg/kg on the recommended daily dose of 42 mg/kg (21 mg/kg two tmes a day). In the clinical trial, the mean daily dose was 35 mg/kg in this population. The effectiveness of lower doses is not studied.

Treatment ought to be initiated with a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg two tmes a day). The daily dose should be increased in 2 weeks by an increment of 20 mg/kg to the recommended daily dose of 50 mg/kg (25 mg/kg two times a day). If a patient cannot tolerate a regular dose of 50 mg/kg, the daily dose might be reduced. In the clinical study, the mean daily dose was 47 mg/kg in this age bracket.

Treatment needs to be initiated with a daily dose of 20 mg/kg by 50 % divided doses (10 mg/kg two times a day). The daily dose should be increased every 14 days by increments of 20 mg/kg to the recommended daily dose of 60 mg/kg (30 mg/kg two tmes a day). If a patient cannot tolerate a day-to-day dose of 60 mg/kg, the daily dose could possibly be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.

For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment needs to be initiated using a daily dose of 500 mg given as two tmes a day dosing (250 mg twice daily). The daily dose needs to be increased every 2 weeks by increments of 500 mg to some maximum recommended daily dose of 1500 mg (750 mg twice daily).

For Keppra tablet dosing in pediatric patients weighing over 40 kg, treatment needs to be initiated with a daily dose of 1000 mg/day given as twice daily dosing (500 mg twice daily). The daily dose needs to be increased every two weeks by increments of 1000 mg/day with a maximum recommended daily dose of 3000 mg (1500 mg two tmes a day).


Partial Onset Seizures
Adults 16 Years And Older

In clinical trials, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were proved to be effective. Although in certain studies there is a propensity toward greater response with higher dose [see Clinical Studies], a consistent surge in response with an increase of dose is not shown.

Treatment ought to be initiated using a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Additional dosing increments could possibly be given (1000 mg/day additional every two weeks) to some maximum recommended daily dose of 3000 mg. Doses more than 3000 mg/day have been utilized in open-label studies for periods of 6 months and longer. There is no evidence that doses greater than 3000 mg/day confer additional benefit.

Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment must be initiated having a dose of 1000 mg/day, given as twice-daily dosing (500 mg two times a day). Dosage should be increased by 1000 mg/day every 14 days on the recommended daily dose of 3000 mg. The effectiveness of doses below 3000 mg/day is not studied.


Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment needs to be initiated which has a dose of 1000 mg/day, given as twice-daily dosing (500 mg two tmes a day). Dosage needs to be increased by 1000 mg/day every 14 days towards the recommended daily dose of 3000 mg. The effectiveness of doses under 3000 mg/day is not adequately studied.


Pediatric Patients Ages 6 To < 16 Years
Treatment needs to be initiated using a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg two times a day). The daily dose must be increased every fourteen days by increments of 20 mg/kg to the recommended daily dose of 60 mg/kg (30 mg/kg two tmes a day). The effectiveness of doses below 60 mg/kg/day will not be adequately studied. Patients with body mass ≤ 20 kg must be dosed with oral solution. Patients with weight above 20 kg might be dosed with either tablets or oral solution. Only whole tablets must be administered.


Adult Patients With Impaired Renal Function
Keppra dosing should be individualized according towards the patient's renal function status.

STORAGE

Store Keppra at room temperature from moisture, heat, and light-weight.

Side Effects

Get emergency medical help in case you have any of these signs and symptoms of a hypersensitivity to Keppra: hives; difficult breathing; swelling of your respective face, lips, tongue, or throat.

Report any new or worsening symptoms to your medical professional, including: mood or behavior changes, depression, anxiety, or in case you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your medical professional at the same time if you use a serious side-effect like:

Less serious Keppra unwanted effects can sometimes include:

This just isn't a complete set of unwanted side effects while others may occur. Tell your physician about any unusual or bothersome side-effect.

Precautions

You should not use Keppra should you are allergic to levetiracetam.

To be sure to can safely take Keppra, tell your physician should you have kidney disease or blood pressure.

You may have thoughts about suicide while investing in this medicine. Tell your doctor if you have signs of depression or suicidal thoughts throughout the first many weeks of treatment, or whenever your dose is changed.

Your family or another caregivers should also be attentive to changes with your mood or symptoms. Your doctor will likely need to check you at regular visits.

FDA pregnancy category C. It isn't known whether Keppra will harm an unborn baby, but creating a seizure during pregnancy could harm the two mother as well as the baby. Tell a medical expert in the event you are pregnant or plan to get pregnant while employing this medication. Do not start or stop taking Keppra during pregnancy without a medical expert's advice. Seizure control is vital during pregnancy. The benefit of preventing seizures may outweigh any risks presented by taking Keppra. Follow your medical professional's instructions about taking Keppra while you are pregnant. Levetiracetam can pass into breast milk and may harm a nursing baby. You should not breast-feed while you're using Keppra. Do not give medicines to your child without the advice of an doctor. Your child's dose needs are based on age and weight. The child should remain under the care of your doctor while using this medicine.

Do not stop using Keppra without first talking to your medical professional, even though you feel awesome. You could have increased seizures in case you stop using Keppra suddenly. You might need to use less and less prior to deciding to stop the medication completely.

You could possibly have thoughts about suicide while taking Keppra. Your doctor should check you at regular visits. Do not miss any scheduled appointments.

Report any new or worsening symptoms to your physician, for example: mood or behavior changes, depression, anxiety, or in the event you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Wear a medical alert tag or carry an ID card praoclaiming that you take Keppra. Any health care bills provider who treats you should know that you take seizure medication.

Keppra may impair your notions or reactions. Be careful should you drive or a single thing that needs you to definitely be alert. Tell a medical expert should you are pregnant or intend to conceive while using this medication. Do not start or stop taking Keppra in pregnancy without your doctor's advice. Having a seizure in pregnancy could harm the two mother as well as the baby. Seizure control is vital in pregnancy as well as the benefits of preventing seizures may outweigh any risks resulting from using Keppra.

Avoid having a drink. It can increase a few of the unwanted side effects of Keppra and may could also increase the chance of seizures. This medication may impair your notions or reactions. Be careful if you drive or a single thing that requires that you be alert.


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