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Uses

INDICATIONS

Imuran is employed to stop rejection of an transplanted kidney. It belongs to the number of medicines known as immunosuppressive agents. Azathioprine will lower the body's natural immunity in patients who receive transplants in order to avoid rejection from the new kidney. It is also accustomed to relieve pain and swelling for patients with rheumatoid arthritis.

INSTRUCTIONS

Use this medicine just as directed because of your doctor. Do not take more of it, or a smaller amount of it, than a medical expert ordered. Taking excessive could raise the potential for unwanted side effects, and taking inadequate won't help your problem.

This medicine is sometimes given in addition to other medicines. If you are utilizing several medicines together, ensure you realize how to take them during the day. Ask your medical professional that will help you plan ways to remember to take your medicines at the right times.

Do not stop investing in this medicine without first checking with your doctor.

Imuran sometimes causes queasiness. Taking this medicine after meals or at bedtime may lessen stomach upset. Talk to your medical professional when you have questions or continue to have difficulties with nausea / vomiting.

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If you miss a dose on this medicine, go on it at the earliest opportunity. However, whether it is almost time for your forthcoming dose, skip the missed dose and return to your normal dosing schedule. Do not double doses.

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DOSAGE

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The dose of this medicine will change for different patients. Follow your medical professional's orders or even the directions on the label. The following information includes just the average doses on this medicine. If your dose differs, tend not to change it unless your doctor lets you know to do so.

The volume of medicine which you take depends around the strength from the medicine. Also, the volume of doses you are taking on a daily basis, time allowed between doses, and also the length of time you're taking the medicine depend for the condition that you are employing the medicine.
For oral dosage form (tablets):
For kidney transplant rejection:

For rheumatoid arthritis symptoms: 

STORAGE 

Store the medicine in a closed container at room temperature, from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of youngsters.
Do not keep outdated medicine or medicine don't needed.
Ask your doctor the method that you should get rid of any medicine you tend not to use.

Side Effects

Along having its needed effects, a medicine could potentially cause some negative effects. Although not most of these side effects may occur, whenever they do occur they could need medical assistance.

Check with your doctor immediately if any in the following side effects occur:


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Some unwanted side effects may occur that always don't need medical help. These negative effects may go away during treatment as your body adjusts towards the medicine. Also, your health care professional may be able to tell you about ways to stop or reduce some of these unwanted side effects. Check with your health care professional if any of the following unwanted side effects continue or are bothersome or for those who have any questions about them:
More common
Nausea or vomiting (mild)
swollen joints
Incidence unfamiliar
Hair loss or thinning from the hair

Other negative effects unlisted may also occur in some patients. If you notice any other effects, check together with your doctor.

Call your doctor for medical health advice about negative effects.

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Precautions

If you will be taking this medicine for years, it is very important that your doctor check you at regular visits for any problems or negative effects which may be due to this medicine. Blood tests are usually necesary to check for unwanted effects.

Using this medicine when you are pregnant can harm your baby. Use an effective form of birth control method to keep from conceiving. If you think you've got get pregnant while using the this medicine, tell your medical professional straight away.

Do not utilize this medicine if you are also taking mercaptopurine (Purinethol®). Using these medicines together could cause serious unwanted side effects.

If you are utilizing azathioprine for arthritis, be sure your medical professional knows should you received chlorambucil (Leukeran®), cyclophosphamide (Cytoxan®, Neosar®), or melphalan (Alkeran®) to take care of your arthritis inside past. Using azathioprine after these medicines may increase your risk for unwanted side effects. Talk to your physician when you have questions on this.

This medicine may increase your chance of getting some kinds of cancer, especially from the skin, lymph system (lymphoma), or blood (leukemia). Talk to your medical professional for those who have concerns relating to this risk.

Use sunscreen or sunblock lotions which has a suncreen factor (SPF) for at least 15 often when you're outdoors. Wear protective clothing and hats, and remain out of sunshine involving the hours of 10 a.m. and 3 p.m. Avoid sunlamps and tanning beds.

While you might be undergoing treatment with azathioprine, and after you stop treatment from it, do not have any immunizations (vaccines) without a medical expert's approval. Azathioprine may lower your body's resistance and the vaccine might not exactly act as well or you'll obtain the infection the vaccine is meant to stop. In addition, you should not be around other persons living in your family who receive live virus vaccines since there is a chance they are able to pass herpes on you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get all-around them and do not stay within the same room with them for very long. If you've questions on this, talk to your physician.

Azathioprine can temporarily lower the amount of white blood cells in your blood, increasing the probability of getting an infection. It can also lower the amount of platelets, that happen to be necessary for proper blood clotting. If this occurs, a number of precautions you'll be able to take, especially when your blood count is low, to reduce the probability of infection or bleeding:

Check with your physician without delay if you have many of these symptoms while you are choosing this medicine: severe nausea / vomiting; diarrhea; fever; rash; an over-all a feeling of discomfort or illness; muscle or pain; lightheadedness or dizziness; or unusual tiredness or weakness. These could be symptoms of the serious reaction towards the medicine in your bowel (intestine).

Do not take other medicines unless they are discussed with a medical expert. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or nutritional vitamin supplements.

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