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INDICATIONS

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Meldonium treats heart ischemia and its particular consequencesis.  It is used in treating brain circulation disorders. Meldonium is believed to improve Mental Processes (Memory, Learning, Focus, Concentration, Processing of Information) and reduces Fatigue, Increases Motivation & Alertness. Meldonium was made to boost Athletic Training & Competitive Performance at the same time as microcirculation & Oxygen Delivery.

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Due to its unique mechanism of action Mildronate, depending on the prescribed dose, is popular for the treating different heart and vascular diseases, also as for the improvement of labor capacity of healthy people at mental and physical overloads and during rehabilitation period.

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INSTRUCTIONS

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Applied internally.

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• Intellectual and physical stress (including in athletes). Adults – 1 g each day
divided into two 500mg doses. Course of treatment is 10-14 days. If necessary, the procedure is repeated in 2-3 weeks.

• Athletes should take 500 mg – 1 g twice a day before training. Duration of
treatment during preparatory period is 2-3 weeks, throughout competition – 10-14 days.

• Cardiovascular disease. As part of combined therapy: 500 mg -1 g (1-2 tablets) every day, using whole dose at once or dividing for 2 takings. Course of treatment is 4-6 weeks.

• Cardialgia contrary to the background of dyshormonal myocardiodystrophy – 500 mg per day. Course of treatment is 12 days.

• Disturbed cerebral circulation. In treatment course after removal of acute disorders: 500 mg – 1 g per day, taking the whole dose at one time or dividing it for two takings. In case of chronic disorders: 500 mg each day. General treatment course is 4-6 weeks. Recurrent courses (usually 2-3 times per year) could possibly be taken after consulting your doctor.

• Diseases of peripheral arteries. 500 mg twice a day.

• Abstinence syndrome in the case of chronic alcoholism. 500 mg 4x each day. Course of treatment is 7-10 days.

• Maximum daily dose is 2000 mg.

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Please confer with your physician prior to using this or some other vitamins and minerals or medications.

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DOSAGE

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Please consult a doctor in connection with required dosage.

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Overdosage
There is no data of cases of Meldonium overdosage. The drug is low-toxic.

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STORAGE 

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Keep from sunlight.
Keep locked and from children.
Store in dry place at room temperature.
Do not exceed storage temperature higher than 25 C

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Side Effects

Rarely - allergy symptoms (redness, rash, itching, oedema), too as dyspepsia, tachycardia, excitement, changes of arterial pressure.

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Precautions

Contraindications:

Hypersensitivity, increased intracranial pressure (in violation of the venous outflow, intracranial tumors).

Restrictions:

Pregnancy, lactation, children under 18 (capsule, injectable solution) or 12 years (syrup), since safety and efficacy are not determined.

Pregnancy and breast-feeding:

Not recommended during pregnancy (safety weren't proven). At the time of treatment should stop breastfeeding (known whether the breast milk gets).

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Interaction along with other drugs along with other forms of interaction

The drug could be joined with antianginal agents, anticoagulants and antiaggregants, antiarrhythmic drugs, diuretics, and bronchial spasmolytics. It intensifies the action of coronary vasodilating drugs, some hypotensive agents, and cardiac glycosides. Taking into consideration the possible progression of mild tachycardia and arterial hypotension, care ought to be taken when combining the drug with nitroglycerin, nifediphine, alpha-adrenoceptor blockers, hypotensive agents and peripheral vasodilators.

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