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Precautions

Do NOT use Estrace if:

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• you are allergic to your ingredient in Estrace

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• you are pregnant or suspect you might be pregnant, have recently given birth or are breast-feeding, or have vaginal bleeding of abnormal or unknown cause

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• you might have known or suspected breast cancers (unless directed because of your doctor) or else you have cancers which can be estrogen-dependent
• you might have blood clots, vein inflammation, or liver disease

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• you experienced a recent stroke or cardiac event.

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Contact a medical expert or doctor straight away if any of these affect you.

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Some medical conditions may communicate with Estrace. Tell your medical professional or pharmacist when you have any health conditions, particularly when any with the following affect you:

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• should you be planning to become pregnant
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• for those who have allergies to medicines, foods, or another substances
• if you have a genealogy of breast cancer, otherwise you have breast lumps or disease, or even an abnormal mammogram

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• for those who have yellowing with the whites of the eyes or skin during pregnancy or with past estrogen use, or hypertension while pregnant (toxemia)

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• in case you have a vaginal infection or womb problems (eg, uterine fibroids/endometriosis, abnormal vaginal bleeding, other uterine problems)

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• in case you have abnormal calcium levels in the blood, asthma, cancer, certain blood disorder (porphyria), cholesterol or lipid problems, depression, diabetes, epilepsy, excessive putting on weight, gallbladder disease, heart problems or any other heart disease, high blood pressure levels, kidney or liver disease, low thyroid alteration in hormones, lupus, migraines, pancreas disease, seizures, or yellowing with the skin or eyes
• in the event you smoke or will likely be having surgery.

Some medicines may interact with Estrace. Tell your doctor if you're taking any other medicines, especially any in the following:

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• Blood thinners (eg, warfarin), corticosteroids (eg, prednisone), succinylcholine, or tacrine his or her actions along with the chance of their unwanted side effects could possibly be increased by Estrace
• Blood thinners (eg, warfarin) his or her effectiveness might be decreased by Estrace
• Barbiturates (eg, phenobarbital), hydantoins (eg, phenytoin), or rifampin because they may decrease Estrace's effectiveness.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Estrace may interact with other medicines that you just take. Check with your health care provider prior to starting, stop, or customize the dose of any medicine.

Important safety information:

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• Estrace could cause dizziness. This effect could possibly be worse in case you go with alcohol or certain medicines. Use Estrace with caution. Do not drive or perform other possible unsafe tasks before you discover how you respond to it.

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• Limit alcohol based drinks if you are taking Estrace.

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• Estrace may cause dark skin patches on your own face (melasma). Exposure to the sun might make these patches darker and you'll need to avoid prolonged exposure to the sun and sunlamps. Consult your medical professional in connection with using sunscreens and protective clothing.
• Estrace might increase the chance of blood clots. The risk could possibly be greater should you smoke (especially in women older than 35 years old).

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• Contact your medical professional if vaginal bleeding of unknown cause occurs. This could be a sign of a significant condition requiring immediate medical help.

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• Contact a medical expert if vaginal discomfort occurs or in the event you suspect you've developed infection while taking Estrace.
• Follow your doctor's instructions for examining your breasts and report any lumps immediately.

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• Additional monitoring of your respective dose or condition could possibly be necessary should you be presently taking an azole antifungal (eg, itraconazole), carbamazepine, a macrolide antibiotic (eg, erythromycin), ritonavir, cimetidine, or St. John's wort.
• If you wear lenses and you develop issues with them, get hold of your doctor.

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• If you is going to be having surgical procedures or will likely be limited to a chair or bed for a long period of your time (eg, a lengthy plane flight), notify a medical expert beforehand. Special precautions may have to be studied during these circumstances while you're taking Estrace.

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• Nonprescription therapy to help prevent bone loss incorporates a weight-bearing fitness program, in addition to adequate daily calcium and vitamin D intake. Consult your medical professional or pharmacist for more details.
• Some of these products might have the dye tartrazine (FD&C Yellow No. 5), that may cause allergies using patients. Consult your medical professional or pharmacist. If you previously had allergic reactions to the dye tartrazine, get hold of your doctor or pharmacist to ascertain when the product you take has the dye tartrazine.

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• Estrace may obstruct certain diagnostic tests. Be sure your doctor and lab personnel know you are taking Estrace.

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• Diabetes patients - Estrace may affect your blood sugar levels. Check blood glucose levels closely. Ask your medical professional before you change the dose of your diabetes medicine.

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• Lab tests, including physical exams and blood pressure levels, may be performed as you use Estrace. You should have breast and pelvic exams, along with a Pap test at least per year. You should also have periodic mammograms as determined because of your doctor. Be sure to keep all doctor and lab appointments.

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• Estrace shouldn't be utilized in children; safety and effectiveness in children haven't been confirmed.

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• Pregnancy and breast-feeding: Do not use Estrace should you be pregnant. Avoid getting pregnant if you are taking it. If you think you may well be pregnant, speak to your doctor immediately. Estrace might be within breast milk. If you are or will probably be breast-feeding whilst you use Estrace, check together with your doctor. Discuss any possible risks in your baby.

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