Clomipramine is used to treat obsessive disorder that is compulsiveOCD). It helps decrease persistent/unwanted thoughts (obsessions), and it assists in easing the urge to perform duplicated tasks (compulsions such as hand-washing, counting, checking) that interfere with everyday living.
This medication belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (serotonin, amongst others) in the mind.
OTHER USES: This section contains uses with this drug which can be not listed in the approved labeling that is professional the drug but that may be prescribed by the health care professional. Use this medication for a condition that is listed in this area only if it is often so prescribed by the health care professional.
This medication has also been utilized to treat depression, panic attacks, and pain that is ongoing.
Read the Medication Guide available from your own pharmacist. Consult your doctor or pharmacist if you have any concerns.
Take this medication by mouth with or without food as directed by your physician. To minimize side-effects such as stomach upset, clomipramine may be started at a dose that is low given in several doses during the day with meals, and slowly increased as your body gets used to it. For you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor after you have reached the best dose. Usually, the dose that is daily not be more than 250 milligrams for grownups and 200 milligrams for kids and teenagers.
Follow your medical practitioner's instructions very carefully. Usually do not just take more or less medication or take it more frequently than prescribed. Your condition will not improve any faster and your threat of adverse effects such as for example seizures may be increased. Dosage is dependant on your condition that is medical and to therapy.
Avoid eating drinking or grapefruit grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more information.
Use this medication regularly in purchase to obtain the most benefit from it. Continue to take it even if you feel well. To help you remember, use it at the same time(s) each time.
Usually do not suddenly stop taking this medication without consulting your physician. Some conditions may be worse when the drug is abruptly stopped. You could experience sweating, dizziness, nausea, vomiting, headache, or irritability if you suddenly stop taking this drug. Your dose may need to be gradually decreased.
It might just take 2 to 3 days or longer prior to the full aftereffects of this medication are noticed. Inform your physician if for example the condition persists or if it worsens.
See section that is also warning.
Dizziness, drowsiness, dry mouth, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety signs may temporarily worsen when you first start taking clomipramine. If any of these effects persist or worsen, notify your pharmacist or doctor quickly.
To alleviate mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or make use of a saliva substitute.
To prevent constipation, maintain a meal plan adequate in fiber, drink plenty of water, and exercise. If you feel constipated while applying this drug, consult with your pharmacist for assist in selecting a laxative (e.g., stimulant-type with stool softener).
Remember that your medical practitioner has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have side that is serious.
Tell your physician right away if some of these unlikely but serious side effects occur: mental/mood modifications (e.g., confusion, depression, memory problems), enlarged/painful breasts, unwanted breast milk manufacturing, irregular/painful menstrual periods, muscle mass stiffness, ringing in the ears, sexual dilemmas (e.g., reduced sexual ability, alterations in desire), shakiness (tremors), numbness/tingling for the hands/feet, trouble urinating.
Tell your doctor immediately if any of these rare but extremely side that is serious occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled motions (especially of this tongue/face/lips), severe stomach/abdominal pain, dark urine, yellowing of eyes/skin.
This medication may increase serotonin and hardly ever cause an extremely serious condition called serotonin syndrome/toxicity. The risk increases you take if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help right away in the event that you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.
Get medical help right away if you have very serious part effects, including: black stools, chest pain, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision modifications (such as seeing rainbows around lights through the night).
A really serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious reaction that is allergic: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is simply not a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.
In america -
Call your medical professional for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your physician for medical advice about adverse effects. You may possibly report side effects to Health Canada at 1-866-234-2345.
Before taking clomipramine, tell your physician or pharmacist if you have any other allergies if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or. This product may contain ingredients that are inactive which can cause allergic reactions or other problems. Confer with your pharmacist for more information.
Before making use of this medication, tell your doctor or pharmacist your medical history, especially of: bloodstream problems (e.g., purpura, thrombocytopenia), breathing problems (e.g., asthma, chronic bronchitis), individual or genealogy and family history of glaucoma (angle-closure type), eating disorders (e.g., bulimia), heart issues (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal issues (e.g., chronic constipation, ileus), liver problems, kidney issues, personal or genealogy and family history of other mental/mood conditions (e.g., manic depression, schizophrenia), history of hospitalization for a very serious response to certain medications (neuroleptic cancerous problem), heartburn/stomach acid within the esophagus (age.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may raise your threat of seizures (e.g., alcohol/sedative dependency, use of electroconvulsive therapy, mind injury/disease), certain kinds of tumors (e.g., pheochromocytoma, neuroblastoma).
Clomipramine may cause a disorder that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause severe (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require medical help immediately.
The danger of QT prolongation may be increased in the event that you have actually certain medical conditions or are taking other drugs that may cause QT prolongation. Before using clomipramine, inform your doctor or pharmacist of the many drugs you take of course you have any one of the following conditions: certain heart disease (heart failure, slow heartbeat, QT prolongation in the EKG), family reputation for certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Lower levels of potassium or magnesium in the blood may increase your risk also of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your physician about utilizing clomipramine safely.
This drug will make you dizzy or drowsy or cause temporary blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit beverages that are alcoholic.
To decrease dizziness and lightheadedness, get up slowly when rising from a seated or lying position.
Before having surgery, tell your dentist or doctor that you are taking this medication.
Caution is advised when working with this medication in children who be involved in active activities since it may increase the risk of heart problems. (See also the Warning section.)
Older adults may be more sensitive to the relative side effects of the drug, especially bleeding, confusion, dizziness, and QT prolongation (see above).
This medication should be used only when demonstrably needed during pregnancy. Newborns exposed to clomipramine during pregnancy might experience withdrawal symptoms or side effects. Tell your doctor right away if you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.
Since untreated mental/mood issues (such as for example obsessive disorder that is compulsive depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.
This medication passes into breast milk and might have undesirable effects on a nursing baby. Consult your doctor before breast-feeding.
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