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Micronase (Glyburide) is definitely an oral diabetes medicine that helps control blood sugar levels.

Glyburide is utilized to take care of diabetes type 2 symptoms.

This medicine is not for treating type 1 diabetes.

Glyburide doubles for other purposes not listed within this medication guide.

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Take just as prescribed because of your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions in your prescription label. Your doctor may occasionally make positive changes to dose to make sure you acquire the best results.

Take glyburide with your first meal of the day, unless your medical professional tells you otherwise.

Your blood glucose levels must be checked often, and you might need other blood tests at your physician's office. Visit your doctor regularly.
Know the warning signs of low blood sugar levels (hypoglycemia) and ways to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a source of sugar obtainable in case you have the signs of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you've severe hypoglycemia and cannot eat or drink, readily injection of glucagon. Your doctor can present you with a prescription to get a glucagon emergency injection kit and tell you the way to give the injection.

Also await signs of blood glucose levels that's too much (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dried-out skin, blurred vision, and fat loss.

Check your blood glucose carefully throughout a time of stress or illness, if you travel, exercise more than usual, are drinking alcohol, or skip meals. These things can impact your blood sugar levels as well as your dose needs may also change.

Your doctor might want you to definitely stop taking glyburide to get a short period of time should you become ill, have a fever or infection, or if you've surgical treatment or a medical emergency.
Ask your doctor how to adjust your glyburide dose as needed. Do not improve your medication dose or schedule without your physician's advice.

If you can find any adjustments to the manufacturer, strength, or sort of glyburide you utilize, your dosage needs may change. Always check your refills to successfully have received the proper brand name and kind of medicine prescribed because of your doctor.

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Take as prescribed because of your doctor.


Store at room temperature, shielded from moisture, heat, and light-weight.


Active ingredient: Glyburide

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Side Effects

Stop using glyburide and get emergency medical help if you might have these warning signs of an allergic reaction: hives; lack of breath; swelling of your respective face, lips, tongue, or throat. Stop taking this medication and call your doctor at the same time if you have all of these serious negative effects:

nausea, stomach pain, low fever, decrease of appetite, dark urine, clay-colored stools, jaundice (yellowing on the skin or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots below your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious unwanted effects may include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete set of side effects and others may occur. Call your medical professional for medical advice about unwanted side effects.


You should avoid using this medication in case you are allergic to glyburide, or:

should you are undergoing treatment with bosentan (Tracleer);

if you might have type 1 diabetes; or

should you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin).

To ensure you can safely take glyburide, tell your physician if you have these other conditions:

hemolytic anemia (a lack of red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

liver or kidney disease;

if you are allergic to sulfa drugs; or

if you've got been using insulin or taking chlorpropamide (Diabinese).

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Certain oral diabetes medications may enhance your risk of serious heart disease. However, not taking care of your diabetes damages your heart and other organs. Talk to a medical expert in regards to the risks and benefits of treating your diabetes with glyburide.

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FDA pregnancy category C. It is not known whether glyburide will harm an child. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication at the duration of delivery. Tell your medical professional should you are pregnant or want to conceive while using the this medication. It is not known whether glyburide passes into breast milk or if it could possibly harm a nursing baby.

Do not use medicines without telling your medical professional should you are breast-feeding a baby. Older adults could be more likely to have low blood glucose levels while taking glyburide.


Important safety information:

You must avoid using this medication in the event you are allergic to glyburide, should you are being treated with bosentan (Tracleer), if you might have type 1 diabetes, or in the event you are in a state of diabetic ketoacidosis (call a medical expert for treatment with insulin).

Before taking glyburide, tell your physician in case you are allergic to sulfa drugs, if you might have been using insulin or chlorpropamide (Diabinese), or if you've hemolytic anemia (a lack of red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care to not let your blood sugar levels get too low. Low blood sugar levels (hypoglycemia) can occur if you skip meals, exercise to much time, are drinking alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets along in case you've got low blood glucose. Other sugar sources include orange juice and milk. Be sure all your family members and pals know the way to help you in a crisis.

Drug interactions

Tell a medical expert about other medications you use, especially:

a blood thinner like warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor such as enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), while others; or

an antibiotic like ciprofloxacin (Cipro), levofloxacin (Levaquin), among others.

Using certain medicines makes it more difficult for that you tell when you have low blood glucose. Tell a medical expert in case you use any of these:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers such as atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), and others.

You could be more likely to have hyperglycemia (high blood sugar) should you take glyburide with:


diuretics (water pills);

steroids (prednisone while others);

phenothiazines (Compazine yet others);

thyroid medicine (Synthroid yet others);

birth control pills and also other hormones;

heart or blood pressure medications (Cartia, Cardizem, Nifedical, Covera, Verelan, yet others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);

seizure medicines (Dilantin among others); and

diet pills or medicines to treat asthma, colds or allergies.

You might be more prone to have hypoglycemia (low blood sugar levels) should you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or blood pressure level medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, among others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or any other salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, while others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists usually are not complete and you will find many other medicines that could increase or minimizing the effects of glyburide on lowering your blood sugar levels. Tell a medical expert about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not find a new medication without telling a medical expert.

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