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Uses

INDICATIONS

Endep can be a tricyclic antidepressant employed to treat depression and chronic pain. Endep raises the signs of depression by correcting the total amount of the chemicals with your brain like norephinephrine and serotonin. These chemicals assist in improving the mood of the patient and manage depression.

INSTRUCTIONS

Use Endep as directed through your doctor.

Endep could be taken with food or before eating anything.
Do not take the medication in larger amounts, or go for more than recommended by your doctor.
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Avoid eating grapefruit or drinking grapefruit juice while taking Endep.
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Do not stop using Endep without first actually talking to your physician. You may need to use less and less before you decide to stop the medication completely. Stopping medicines suddenly may cause that you have unpleasant unwanted effects.
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Endep will take around 1 month to control the signs of depression. Continue to work with Endep although you may feel well. Do not miss any doses.
Talk with a medical expert if your symptoms do not improve after 4 weeks of treatment.
If you'll want any kind of surgery, tell the surgeon in advance that you're taking Endep. You may need to stop while using the medicine to get a small amount of time.
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If you miss a dose of Endep, go as quickly as possible. If it is almost time for your forthcoming dose, skip the missed dose and go back to your normal dosing schedule. Do not take 2 doses simultaneously.
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DOSAGE

The dosage for Endep depends upon the condition with the patient. Only the doctors can select from simply how much the dosage needs to be directed at an individual. Usually a low dose of Endep emerges in a certain period and definately will gradually increase according to the tolerance and improvement in the patient.
Initial dosage usually starts at 75 milligrams around 159 milligrams a day which can be divided in smaller doses. For confined patients in hospitals, doctors usually administer 100 to 200 milligrams a day.
Elderly patients are usually furnished with low dosage being that they are not capable of the tolerance because of the age. Doctors usually lessen the dosage as the individual improves. Constant monitoring in the patient’s condition is necessary so as to see whether the dosage ought to be increased or decreased.

Ask your medical provider any queries you may have regarding how to work with Endep.

STORAGE

Endep should be stored at room temperature faraway from moisture and sunlight. Avoid storage at temperatures above 30°C (86°F). Keep Endep out with the reach of youngsters.

MORE INFO:

Active ingredient: Amitriptyline.

Amitriptyline was approved by the FDA in May 1983.

Side Effects

All medicines could cause negative effects, however, many folks have no, or minor, negative effects.

Check with a medical expert if these most frequent side effects persist or become bothersome:

Blurred vision; alteration of libido or ability; constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; loss of appetite; nausea; tiredness; trouble sleeping; weakness.

Seek medical assistance straight away if all of these severe unwanted side effects occur:

Severe hypersensitive reactions (rash; hives; itching; difficulty breathing; tightness inside chest; swelling in the mouth, face, lips, or tongue); chest pain; confusion; dark urine; delusions; difficulty speaking or swallowing; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; new or worsening agitation, anxiety, anxiety attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated feeling of well-being, restlessness, or inability to sit still; numbness or tingling within an arm or leg; one-sided weakness; seizures; severe or persistent dizziness or headache; severe or persistent sleep disorders; slurred speech; suicidal thoughts or actions; tremor; trouble urinating; uncontrolled muscle movements (eg, of face, tongue, arms, legs); unusual bleeding or bruising; unusual or severe mental or mood changes; vision problems; yellowing from the skin or eyes.

This is not a complete report on all unwanted side effects that could occur. If you might have questions regarding side effects, contact your medical provider.

Precautions

Do NOT use Endep if:

you are allergic to the ingredient in Endep
you are currently taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine, selegiline) within the past 14 days
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you take antihistamines (eg, diphenhydramine), cisapride, droperidol, a ketolide (eg, telithromycin) , a macrolide (eg, erythromycin), mibefradil, or pimozide
you are recovering from a heart attack.
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Contact your medical professional or doctor immediately if some of these affect you.

Some medical conditions may interact with Endep. Tell your doctor or pharmacist for those who have any health concerns, particularly if any of the following affect you:

if you are pregnant, about to conceive, or are breast-feeding
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if you have a history of mental illness (eg, bipolar disorder, mania, manic-depression), or consider or attempted suicide
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when you have glaucoma, an irregular heartbeat, cardiovascular disease, chest pain, liver disease, prostate problems, thyroid disease, or can't seem to urinate (urinary retention)
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Some medicines may connect to Endep. Tell your doctor if you are taking another medicines, especially any in the following:

MAOIs (eg, phenelzine, selegiline) simply because they may cause serious, sometimes life-threatening, reactions. Do not take MAO inhibitors with, or within fourteen days of taking, Endep
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Anticholinergics (eg, scopolamine), bupropion, cimetidine, fluconazole, phenothiazines (eg, chlorpromazine), SSRIs (eg, fluoxetine), terbinafine, or valproic acid because unwanted effects like blurred vision, difficult urination, drowsiness or sedation, dry mouth, or lightheadedness may occur
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Antihistamines (eg, diphenhydramine), cisapride, droperidol, ketolides (eg, telithromycin), macrolides (eg, erythromycin), mibefradil, pimozide, or streptogramins (eg, quinupristin/dalfopristin) because serious unwanted side effects around the heart (eg, racing heartbeat, dizziness, fainting, life-threatening abnormal heartbeat resulting in unconsciousness, and insufficient heartbeat, could possibly be increased by Endep
Carbamazepine, thyroid medicines (eg, levothyroxine), or stimulants (eg, albuterol, pseudoephedrine) because their unwanted side effects could be increased by Endep
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Warfarin because unwanted effects including serious bleeding may be increased by Endep
Clonidine, guanethidine, or guanfacine because the effectiveness of the medicines may be decreased.
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This will not be a total set of all interactions that could occur. Ask your medical provider if Endep may communicate with other medicines which you take. Check with your health care provider when you start, stop, or alter the dose of the medicine.

Important safety information:

Endep may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything whatsoever else that could be dangerous until you know how you reply to Endep. Using Endep alone, with medicines, or with alcohol may lessen your skill to drive or perform other very dangerous tasks.
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Avoid drinking alcohol or taking other medicines that create drowsiness (eg, sedatives, tranquilizers) while taking Endep. Endep will add towards the connection between alcohol and also other depressants. Ask the pharmacist if you have questions regarding which medicines are depressants.
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Endep could cause dizziness, lightheadedness, or fainting; alcohol, warm weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, specially in the morning. Sit or lie down at the first symbol of all of these effects.
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Involuntary and uncontrollable movements may develop in patients taking Endep. Occurrence is highest one of the elderly, especially women. The risk of developing these involuntary movements along with the likelihood they will become permanent are increased with long-term use along with high doses. However, it is possible to develop these symptoms after short-term use at low doses. Contact your medical provider immediately if any of the following occur: involuntary movements from the tongue, face, mouth, or jaw (eg, protrusion of tongue, puffing of cheeks, puckering of mouth, chewing movements), sometimes associated with involuntary movements from the legs and arms.
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Endep could cause sensitivity to sunlight. Avoid prolonged exposure for the sun along with other ultraviolet light (eg, tanning beds). Use sunscreens and wear protective clothing until tolerance is established.
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Do not become overheated in hot weather or during exercise and other activities since heatstroke may occur.
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Diabetes patients - Endep may affect your blood glucose. Check blood sugar levels levels closely. Ask your doctor prior to deciding to customize the dose of your respective diabetes medicine.
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Before you have any medical or dental treatments, emergency care, or surgery, tell your physician or dentist that you will be using Endep.
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Use caution in the elderly; they might be more sensitive to its effects, especially lightheadedness upon standing; rapid heartbeat; breathing problems; difficult urination; and constipation.
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Pregnancy and breast-feeding: Endep has been shown to cause harm to the human fetus. If you plan on becoming pregnant, consult with your doctor the huge benefits and perils of using Endep while pregnant. Endep is excreted inside breast milk. Do not breastfeed while taking Endep.
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