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Precautions

Do NOT use Amaryl if:

• you happen to be allergic to any ingredient in Amaryl
• you've got certain severe problems linked to diabetes (eg, diabetic coma, diabetic ketoacidosis)
• you have moderate to severe burns, or quite high blood acid levels (acidosis)
• you consider bosentan.

Contact your doctor or health care provider immediately if these affect you.

Some medical conditions may communicate with Amaryl. Tell your medical professional or pharmacist when you have any medical conditions, particularly if any with the following apply to you:

• if you're pregnant, about to conceive, or are breast-feeding
• in the event you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or any other substances
• in case you have had an intense allergic reaction (eg, an intense rash, hives, breathing difficulties, dizziness) to your other sulfonamide medicine, such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glipizide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide
• for those who have a good reputation for stroke or liver, kidney, thyroid, heart, or blood vessel problems
• when you have stomach or bowel problems (eg, stomach or bowel blockage, stomach paralysis), are drinking alcoholic beverages, or have had poor nutrition
• in case you have type 1 diabetes, anemia, inadequate health, a top fever, an intense infection, severe diarrhea, high blood acid levels, or experienced a serious injury
• in case you have low levels of your enzyme called glucose 6-phosphate dehydrogenase (G6PD)
• when you have a history of certain hormonal problems (eg, adrenal or pituitary problems, syndrome of inappropriate secretion of antidiuretic hormone [SIADH]), or low blood sodium levels
• if you will end up having surgery.

Some medicines may connect to Amaryl. Tell your doctor should you consider any other medicines, especially any of the following:

• Bosentan because liver problems may occur; the strength of both medicines might be decreased
• Beta-blockers (eg, propranolol) because the likelihood of low blood sugar could possibly be increased. They may also hide certain signs of low blood glucose and earn it harder to notice
• Anticoagulants (eg, warfarin), azole antifungals (eg, miconazole, ketoconazole), chloramphenicol, clarithromycin, clofibrate, fenfluramine, insulin, metformin, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), phenylbutazone, probenecid, quinolone antibiotics (eg, ciprofloxacin), salicylates (eg, aspirin), or sulfonamides (eg, sulfamethoxazole) because the likelihood of low blood glucose might be increased
• Corticosteroids (eg, prednisone), decongestants (eg, pseudoephedrine), diazoxide, diuretics (eg, furosemide, hydrochlorothiazide), estrogens, hormonal contraceptives (eg, birth control pills), isoniazid, niacin, phenothiazines (eg, promethazine), phenytoin, rifamycins (eg, rifampin), sympathomimetics (eg, albuterol, epinephrine, terbutaline), or thyroid supplements (eg, levothyroxine) because they may decrease Amaryl's effectiveness, resulting in high blood sugar levels
• Gemfibrozil because blood sugar levels could be increased or decreased.

This will not be a total report on all interactions that could occur. Ask your doctor if Amaryl may interact to medicines that you simply take. Check with your medical provider before starting, stop, or alter the dose associated with a medicine.

Important safety information:

• Amaryl may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects could be worse if you go with alcohol or certain medicines. Use Amaryl with caution. Do not drive or perform other possible unsafe tasks until you understand how you answer it.
• Do not consume alcohol when you consider Amaryl; it could increase the likelihood of low blood glucose. Rarely, alcohol may talk with Amaryl and cause a serious reaction with symptoms such as flushing, nausea, vomiting, dizziness, or stomach pain. Discuss questions or concerns with your medical professional.
• Proper diet, regular exercise, and regular blood sugar levels testing are important for best results with Amaryl. Follow the diet and exercise program provided to you by your physician.
• It might be harder to regulate your blood glucose during times of stress for example fever, infection, injury, or surgery. Talk with your doctor about how precisely to control your blood glucose if some of these occur. Do not change the dose of your medicine without checking with your medical professional.
• Amaryl may cause low blood sugar levels. Low blood sugar will make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also build your heart rhythm faster; build your vision change; give you a headache, chills, or tremors; or cause you to be more hungry. It is often a good plan to hold a dependable source of glucose (eg, tablets or gel) to treat low blood glucose levels. If this is not available, you must eat or drink a fast method to obtain sugar like table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood glucose level quickly. Tell your physician straight away in such a circumstance. To prevent low blood glucose, eat meals at the same time on a daily basis and never skip meals.
• Risk of low blood sugar levels might be increased by severe or prolonged exercise, alcohol consumption, or skipping meals.
• Amaryl may cause you to become sunburned quicker. Avoid the sun, sunlamps, or tanning booths and soon you know how you respond to Amaryl. Use a sunscreen or wear protective clothing if you should be outside for more than a limited time.
• Tell your physician or dentist that you just take Amaryl when you get any medical or dentistry, emergency care, or surgery.
• Lab tests, including fasting blood glucose and hemoglobin A_1c, could be performed while you use Amaryl. These tests may be used to monitor your complaint or check for side effects. Be sure to keep all doctor and lab appointments.
• Use Amaryl with caution inside the elderly; they could possibly be more sensitive to its effects, especially low blood sugar levels.
• Amaryl must be used in combination with extreme care in children; safety and effectiveness in children have not been confirmed.
• Pregnancy and breast-feeding: Amaryl could cause problems for the fetus or newborn. If you conceive, contact your doctor. You will need to discuss the advantages and risks of using Amaryl while you're pregnant. It is not known if Amaryl is found in breast milk. Do not breastfeed while taking Amaryl.

When employed for extended periods of time, Amaryl may not be well. If your blood glucose levels has been in order and after that becomes difficult to manage, contact your physician. Do not change the dose of your respective medicine without checking with your medical professional.