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Precautions

Do NOT use Amaryl if:

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• you've got certain severe problems linked to diabetes (eg, diabetic coma, diabetic ketoacidosis)

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• you've moderate to severe burns, or quite high blood acid levels (acidosis)

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Contact your doctor or health care provider straight away if these apply to you.

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Some medical conditions may connect to Amaryl. Tell your physician or pharmacist for those who have any health conditions, in particular when any with the following connect with you:

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• when you have allergies to medicines, foods, or another substances
• when you have had a serious hypersensitive reaction (eg, a severe rash, hives, the like, dizziness) to any other sulfonamide medicine, like acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glipizide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide

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• in case you have a good stroke or liver, kidney, thyroid, heart, or circulation system problems

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• when you have stomach or bowel problems (eg, stomach or bowel blockage, stomach paralysis), consume alcohol, or experienced poor nutrition
• in case you have type 1 diabetes, anemia, inadequate health, a higher fever, an extreme infection, severe diarrhea, high blood acid levels, or have experienced a serious injury
• for those who have 'abnormal' amounts associated with an enzyme called glucose 6-phosphate dehydrogenase (G6PD)

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• when you have a history of certain hormonal problems (eg, adrenal or pituitary problems, syndrome of inappropriate secretion of antidiuretic hormone [SIADH]), or low blood sodium levels
• if you may be having surgery.

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Some medicines may talk with Amaryl. Tell your health care provider in case you are taking every other medicines, especially any of the following:

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• Bosentan because liver problems may occur; the strength of both medicines could possibly be decreased

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• Beta-blockers (eg, propranolol) since the probability of low blood sugar levels could be increased. They may also hide certain indications of low blood glucose levels and make it harder to notice

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• Anticoagulants (eg, warfarin), azole antifungals (eg, miconazole, ketoconazole), chloramphenicol, clarithromycin, clofibrate, fenfluramine, insulin, metformin, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), phenylbutazone, probenecid, quinolone antibiotics (eg, ciprofloxacin), salicylates (eg, aspirin), or sulfonamides (eg, sulfamethoxazole) since the probability of low blood glucose could be increased

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• Corticosteroids (eg, prednisone), decongestants (eg, pseudoephedrine), diazoxide, diuretics (eg, furosemide, hydrochlorothiazide), estrogens, hormonal contraceptives (eg, birth control pills), isoniazid, niacin, phenothiazines (eg, promethazine), phenytoin, rifamycins (eg, rifampin), sympathomimetics (eg, albuterol, epinephrine, terbutaline), or thyroid supplements (eg, levothyroxine) because they may decrease Amaryl's effectiveness, resulting in high blood sugar levels

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This might not be a whole list of all interactions that could occur. Ask your health care provider if Amaryl may interact along with other medicines that you just take. Check with your doctor before starting, stop, or alter the dose of the medicine.

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Important safety information:

• Amaryl could potentially cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects could be worse if you go on it with alcohol or certain medicines. Use Amaryl with caution. Do not drive or perform other possible unsafe tasks before you discover how you respond to it.

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• Do not drink alcohol whilst you consider Amaryl; it may raise the chance of low blood glucose levels. Rarely, alcohol may interact with Amaryl and spark a serious reaction with symptoms such as flushing, nausea, vomiting, dizziness, or stomach pain. Discuss any queries or concerns with your medical professional.

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• Proper diet, routine workouts, and regular blood glucose levels testing are crucial for the most powerful results with Amaryl. Follow the diet and exercise program directed at you from your doctor.

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• It may be harder to manage your blood glucose during periods of stress like fever, infection, injury, or surgery. Talk with your physician about how exactly to manage your blood glucose levels if all of these occur. Do not change the dose of your medicine without checking with your physician.

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• Amaryl might cause low blood sugar levels. Low blood sugar will make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart rhythm faster; you could make your vision change; give you a headache, chills, or tremors; or cause you to more hungry. It is often a wise decision to handle a trusted source of glucose (eg, tablets or gel) to take care of low blood glucose. If this is not available, you must eat or drink a simple method to obtain sugar like countertop sugar, honey, candy, orange juice, or non-diet soda. This will increase your blood sugar levels level quickly. Tell your doctor without delay should this happen. To prevent low blood sugar, eat meals simultaneously each day and do not skip meals.

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• Risk of low blood sugar levels might be increased by severe or prolonged exercise, having a drink, or skipping meals.
• Amaryl could potentially cause you to become sunburned easier. Avoid the sun, sunlamps, or tanning booths until you know how you answer Amaryl. Use a sunscreen or wear protective clothing in case you should be outside for more than a limited time.

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• Tell your medical professional or dentist that you just take Amaryl when you get any medical or dentistry, emergency care, or surgery.

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• Lab tests, including fasting blood sugar levels and hemoglobin A_1c, may be performed as you use Amaryl. These tests could be used to monitor your trouble or search for side effects. Be sure to keep all doctor and lab appointments.

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• Use Amaryl with caution in the elderly; they may be more responsive to its effects, especially low blood sugar levels.

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• Amaryl ought to be combined with careful attention in youngsters; safety and effectiveness in kids weren't confirmed.
• Pregnancy and breast-feeding: Amaryl could potentially cause harm to the fetus or newborn. If you conceive, contact your physician. You will need to discuss the rewards and perils associated with using Amaryl while you are pregnant. It is not known if Amaryl can be found in breast milk. Do not breastfeed while taking Amaryl.

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When used by long periods of time, Amaryl might not be well. If your blood sugar levels has been in check and after that becomes challenging to manage, contact your medical professional. Do not customize the dose of one's medicine without checking with your medical professional.

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