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Ponstel (Mefenamic Acid) is a small grouping of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Mefenamic acid functions by reducing hormones that cause inflammation and pain within the body.

Mefenamic acid is employed to deal with pain or inflammation due to arthritis. It is also used to help remedy menstrual pain.

Mefenamic acid doubles for other purposes not listed within this medication guide.

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Take prescription drugs just as it was prescribed to suit your needs. Do not take the medication in larger amounts, or go more than recommended from your doctor. Follow the directions on your prescription label.

If you take mefenamic acid for long periods of time, your medical professional may choose to check yourself regularly to make sure this medication isn't causing harmful effects. Do not miss any scheduled visits to a medical expert.

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Take the medicine as directed by your doctor.

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Seek emergency medical help if you think maybe you might have accustomed to much of this medicine. Overdose symptoms might include nausea, vomiting, stomach pain, dizziness, drowsiness, black or bloody stools, coughing up blood, urinating less than usual or otherwise in any way, shallow breathing, fainting, or coma.

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Store mefenamic acid at room temperature, away from moisture, heat, and light.

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Active Ingredient: Mefenamic Acid

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Side Effects

Get emergency medical help if you have these signs of a hypersensitive reaction: hives; breathlessness; swelling of one's face, lips, tongue, or throat.

Stop taking mefenamic acid and seek medical assistance or call a medical expert at the same time if you might have these serious negative effects:

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chest pain, weakness, shortness of breath, slurred speech, issues with vision or balance;

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black, bloody, or tarry stools, paying up blood or vomit that appears like coffee grounds;

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urinating less than usual or otherwise at all;

pain, burning, or bleeding once you urinate;

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nausea, stomach pain, low fever, lack of appetite, dark urine, clay-colored stools, jaundice (yellowing of the epidermis or eyes);

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fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or

bruising, severe tingling, numbness, pain, muscle weakness.

Less serious negative effects can sometimes include:

upset stomach, mild heartburn or stomach pain, diarrhea, constipation; bloating, gas;

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dizziness, headache, nervousness;

skin itching or rash;

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increased sweating, runny nose;

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blurred vision; or

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ringing within your ears.

This just isn't a complete list of side effects yet others may occur. Call your physician for medical health advice about side effects.

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This medicine can enhance your probability of life-threatening heart or circulation problems, including cardiac arrest or stroke. Do not use this medicine right before or after having heart bypass surgery (also called cardio-arterial bypass graft, or CABG).

Seek emergency medical help if you've got signs of heart or circulation problems, including chest pain, weakness, breathlessness, slurred speech, or problems with vision or balance.

This medicine can also enhance your chance of serious effects for the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions might be fatal and gastrointestinal effects may appear without warning without notice when you are taking mefenamic acid. Older adults might have far greater chance of these serious gastrointestinal side effects.

Call your medical professional at the same time if you might have signs and symptoms of bleeding inside your stomach or intestines. This includes black, bloody, or tarry stools, or paying up blood or vomit that looks like coffee grounds.

Do not use some other over-the-counter cold, allergy, or pain medication without first asking a medical expert or pharmacist.

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Do not consume alcohol while taking mefenamic acid. Alcohol can boost the chance of stomach bleeding.

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Important safety information: 

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Tell your doctor if you are taking an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor). Taking these drugs with mefenamic acid may lead you to bruise or bleed easily.

Before taking mefenamic acid, tell a medical expert should you be taking any of the following drugs:

a blood thinner like warfarin (Coumadin);

a diuretic (water pill) like furosemide (Lasix);

cyclosporine (Gengraf, Neoral, Sandimmune);

lithium (Eskalith, Lithobid);

methotrexate (Rheumatrex, Trexall);

steroids (prednisone yet others); or

aspirin or NSAIDs (non-steroidal anti-inflammatory drugs) including diclofenac (Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Advil, Motrin), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), meclofenamate (Meclomen), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), among others.

This list is not complete where there might be other drugs that may interact with mefenamic acid. Tell your medical professional about each of the prescription and over-the-counter medications you employ. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not employ a new medication without telling your medical professional.

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