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Mestinon (Pyridostigmine) affects chemicals by the body processes which might be involved in the communication between nerve impulses and muscle movement.

Pyridostigmine is used to help remedy the signs and symptoms of myasthenia gravis. It is also used in military personnel who've been subjected to nerve gas.

Pyridostigmine could also be used for purposes unpublished in this medication guide.


Take just as prescribed from your doctor. Do not take in larger or smaller amounts and more than recommended. Follow the directions on the prescription label.
Take this medicine with food or milk when it upsets your stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill might cause too much of the drug to be sold previously.

Measure liquid medicine having a special dose measuring spoon or medicine cup, not using a regular table spoon. If you do not have a very dose measuring device, ask your friendly phamacist first.

The amount and timing of this medicine is vitally important on the success of one's treatment. Carefully follow your medical professional's instructions about how much medicine to take so when to look at it.

Your doctor may occasionally change your dose to make sure you acquire the best results. You may be asked to keep a daily record of once you took each dose and exactly how long the results lasted. This will help your physician decide if your dose should be adjusted.
If you need surgery, tell the surgeon ahead of time that you're using pyridostigmine. You may need to stop while using the medicine to get a short period of time. Store at room temperature faraway from moisture and also heat.


Take the medicine as prescribed because of your doctor.


Keep the tablets within their original container, combined with the canister of moisture-absorbing preservative that accompany this medicine.


Active ingredient: Pyridostigmine

Side Effects

Get emergency medical help if you have some of these warning signs of an allergic reaction: hives; difficulty breathing; swelling of your respective face, lips, tongue, or throat. Stop using pyridostigmine and call your medical professional at once for those who have any of these serious negative effects:

extreme muscle weakness, muscle twicthing;

slurred speech, vision problems;

severe vomiting or diarrhea;

cough with mucus;

confusion, anxiety, panic attacks;

seizure (convulsions); or

worsening or no improvement with your signs and symptoms of myasthenia gravis.

Less serious unwanted effects can sometimes include:

cold sweat, pale skin;

urinating more than usual;

watery eyes;

mild nausea, vomiting, or upset stomach;

warmth or tingly feeling; or

mild rash or itching.

This is not a complete report on unwanted effects while others may occur. Call your doctor for health advice about negative effects.


You must avoid using pyridostigmine in case you are allergic to it, or if you use a bladder or bowel obstruction.

To make sure you can safely take pyridostigmine, tell a medical expert if you have all of these other difficulties:


kidney disease;

an ulcer or other serious stomach disorder;

high blood pressure level, coronary disease;

overactive thyroid; or

a good reputation for seizures.

It is just not known whether pyridostigmine will harm an unborn baby. Tell your physician if you are pregnant or prefer to conceive with all the prescription drugs. It is just not known whether pyridostigmine passes into breast milk or whether it could harm a nursing baby. Do not use this medication without telling a medical expert if you are breast-feeding a baby.

Drugs interaction 

Tell your physician about other medicines you have, especially:

atropine (Atreza, Sal-Tropine);

belladonna (Donnatal, yet others);

benztropine (Cogentin);

clidinium (Quarzan);

clozapine (Clozaril, FazaClo);

dimenhydrinate (Dramamine);

methscopolamine (Pamine), scopolamine (Transderm Scop);

glycopyrrolate (Robinul);

mepenzolate (Cantil);

bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

bronchodilators for example ipratropium (Atrovent) or tiotropium (Spiriva);

cold medicine, allergy medicine, or sleeping pills that contain an antihistamine such as diphenhydramine (Tylenol PM) or doxylamine (Unisom);

heart rhythm medication for example quinidine (Quin-G), procainamide (Procan, Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), and others;

irritable bowel medications for example dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);

medicine to take care of Alzheimer's dementia, such as donepezil (Aricept), rivastigmine (Exelon), or tacrine (Cognex); or

a steroid such as betamethasone (Celestone) or dexamethasone (Cortastat, Dexasone, Solurex, DexPak).

This list isn't complete along with other drugs may talk with pyridostigmine. Tell your physician about all medications you have. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling a medical expert.

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