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Indinavir is surely an antiviral medication in the band of HIV medicines called protease (PRO-tee-ayz) inhibitors. Indinavir prevents human immunodeficiency virus (HIV) cells from multiplying within your body. It is utilized to treat HIV, which then causes acquired immunodeficiency syndrome (AIDS). Indinavir just isn't a cure for HIV or AIDS.


Take indinavir just as it had been prescribed for you. Do not consider the medication in larger amounts, or get it more than recommended through your doctor. Follow the directions on your own prescription label.

This medication incorporates patient instructions for secure and efficient use. Follow these directions carefully. Ask your medical professional or pharmacist if you have any questions.
Take indinavir which has a full glass (8 ounces) of water or skim milk. You may also drink juice, coffee, or tea using this type of medication. Drink at the very least 6 associated with water each day to prevent kidney stones when you are taking indinavir. Indinavir ought to be taken on an empty stomach, at least 1 hour before or 2 hours following a meal.

If you'd like to make medication with food, eat only a light meal, such as dry toast with jelly, or corn flakes with skim milk and sugar. Avoid eating a high-fat meal.

It is important to make use of indinavir regularly to find the most benefit. Get your prescription refilled before you run out of medicine completely.

To make sure this medication is assisting your problem, your blood must be tested often. Your liver function may also should be tested. Do not miss any scheduled visits to your medical professional.

HIV/AIDS is normally treated with a combination of different drugs. To best treat your problem, use all of the medications as directed through your doctor. Be sure to see the medication guide or patient instructions supplied with each of one's medications. Do not alter your doses or medication schedule without advice from your physician. Every person with HIV or AIDS should remain underneath the care of your doctor.

Take the missed dose when you remember and take your following dose at the regularly scheduled time. If you are a lot more than 120 minutes late in taking your indinavir, skip the missed dose and make next regularly scheduled dose. Do not take extra medicine to produce the missed dose.


Usual Adult Dose for HIV Infection
800 mg orally every 8 hours or indinavir 800 mg plus ritonavir 100 mg to 200 mg orally every 12 hours.

Usual Adult Dose for Nonoccupational Exposure
800 mg orally every 8 hours or indinavir 800 mg plus ritonavir 100 mg to 200 mg orally every 12 hours.
Duration: Prophylaxis must be initiated at the earliest opportunity, within 72 hours of exposure, and continued for 28 days.
Indinavir plus ritonavir plus 2 NRTIs is probably the alternative regimens suited to nonoccupational postexposure HIV prophylaxis.

Usual Adult Dose for Occupational Exposure
800 mg orally every 8 hours 800 mg orally every 8 hours plus lamivudine-zidovudine,
or indinavir 800 mg plus ritonavir 100 mg to 200 mg orally every 12 hours plus lamivudine-zidovudine.
Duration: Therapy should start promptly, preferably within 1 to 2 hours postexposure. The exact time period of therapy may vary in line with the institution's protocol.

Liver Dose Adjustments
Mild to moderate hepatic insufficiency: 600 mg orally every 8 hours.

Dose Adjustments
Consider reducing the dose to 600 mg every 8 hours if delavirdine, itraconazole, or ketoconazole are administered concomitantly. Increase the dose to 1000 mg every 8 hours if rifabutin is offered concurrently, and decrease the rifabutin dose by half.

Strict adherence towards the prescribed dose is vital. Patients ought not modify the dose or discontinue therapy without consulting their physician.

Adequate hydration (1.5 liters/day) is crucial during therapy to relieve the chance of nephrolithiasis. A brief interruption (usually 1 to 3 days) or total discontinuation could possibly be necessary if nephrolithiasis occurs.

Discontinue indinavir if hemolytic anemia occurs. Consider discontinuation if severe leukocyturia develops.


Store indinavir at room temperature from moisture and also heat. Keep the capsules in their original container, with the packet of moisture-absorbing preservative that comes with indinavir capsules.

Side Effects

Get emergency medical help if you have any of these indications of a hypersensitive reaction: hives; breathlessness; swelling of the face, lips, tongue, or throat. Stop taking indinavir and call a medical expert immediately if you have these serious unwanted side effects:

Less serious unwanted effects can include:

This is just not a complete listing of unwanted side effects yet others may occur. Tell your doctor about any unusual or bothersome side-effect.


Do not take prescription drugs should you be allergic to indinavir.
Do not take indinavir with amiodarone (Cordarone, Pacerone), cisapride (Propulsid), pimozide (Orap), alprazolam (Xanax), oral midazolam (Versed), triazolam (Halcion), or ergot medicines for example ergotamine (Ergomar, Cafergot), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), or methylergonovine (Methergine). These drugs might cause life-threatening unwanted side effects the use of them if you are taking indinavir.

Before taking indinavir, tell a medical expert in case you are allergic to the drugs, or when you have:

If you might have some of these conditions, you will need a dose adjustment or special tests to soundly take indinavir.
FDA pregnancy category C. This medication may be unhealthy for an unborn baby. Tell your doctor if you are pregnant or intend to get pregnant during treatment. HIV may be passed on the baby in the event the mother is not properly treated in pregnancy. Take all of the HIV medicines as directed to overcome your infection when you are pregnant.

Your name may have to be for auction on an antiviral pregnancy registry once you begin using medicines.
You ought not breast-feed if you are using indinavir. Women with HIV or AIDS shouldn't breast-feed whatsoever. Even if your baby is born without HIV, you may still pass the herpes simplex virus to the baby in your breast milk.

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