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Tofranil (Imipramine) is in a group of drugs called tricyclic antidepressants. Imipramine affects chemicals within the brain that could become unbalanced.
It can be used to treat signs of depression.
This medicine could also be used for purposes besides those classified by prescription drugs guide.


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Take medicines the same manner it was prescribed to suit your needs. Do not make medication in larger amounts, or go for more than recommended by your doctor. Your doctor may occasionally alter your dose to successfully obtain the best results from prescription drugs. Follow the directions on your own prescription label.
If you might want any kind of surgery, tell the surgeon ahead of time that you're taking imipramine. You may need to stop while using the medicine for a small amount of time.
Do not stop using imipramine without first conversing with your medical professional. You may need to use much less when you stop the medication completely. Stopping medicines suddenly could cause one to have unpleasant unwanted effects. It may take as much as 30 days of using this medicine before your symptoms improve. For best results, keep while using medication as directed. Talk with your physician if your symptoms tend not to improve after 3 weeks of treatment.

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If you missed the dose go once you remember. If it really is almost time for your next dose, skip the missed dose and take the medicine with the next regularly scheduled time. Do not take extra medicine to produce the missed dose.

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Seek emergency medical help if you believe you've got used an excessive amount of this medicine. An overdose of imipramine might be fatal.
Symptoms of your imipramine overdose may include uneven heartbeats, extreme drowsiness, agitation, vomiting, blurred vision, sweating, muscle stiffness, swelling, breathlessness, blue lips or fingernails, feeling light-headed, fainting, seizure (convulsions), or coma.


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Take this medicine as prescribed through your doctor.

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Store imipramine at room temperature far from moisture and warmth.


Active Ingredient: Imipramine

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Tofranil is a tricyclic antidepressant. It works by improving the activity of certain chemicals inside brain which help elevate mood.

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Side Effects

Get emergency medical help if you've these signs of your allergic reaction: hives; breathlessness; swelling of your face, lips, tongue, or throat.

Call your physician immediately if you've any new or worsening symptoms including: mood or behavior changes, anxiety, panic disorder, trouble sleeping, or if you're feeling impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

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Call your doctor at the same time if you might have any of these serious unwanted side effects:

fast, pounding, or uneven heart rate;

chest pain or heavy feeling, pain spreading on the arm or shoulder, nausea, sweating, general ill feeling;

sudden numbness or weakness, especially on one hand in the body;

sudden headache, confusion, issues with vision, speech, or balance;

feeling short of breath, despite having mild exertion;

swelling, rapid fat gain;

confusion, hallucinations, or seizure (convulsions);

easy bruising or bleeding, unusual weakness;

restless muscle movements inside your eyes, tongue, jaw, or neck;

urinating pretty much than usual;

extreme thirst with headache, nausea, vomiting, and weakness;

skin rash, bruising, severe tingling, numbness, pain, or muscle weakness.

Less serious unwanted effects could possibly be more prone to occur, like:

nausea, vomiting, stomach pain, lack of appetite;

constipation or diarrhea;

dry mouth, unpleasant taste;

weight changes;

weakness, not enough coordination;

feeling dizzy, drowsy, or tired;


blurred vision, headache, ringing with your ears;

breast swelling (in males or women); or

decreased sexual drive, impotence, or difficulty through an orgasm.

Tofranil will be used only through the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your medical professional.

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Do not use Tofranil if:

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you happen to be allergic to your ingredient in Tofranil;

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you have taken furazolidone or perhaps a monoamine oxidase inhibitor (MAOI) (e.g., phenelzine) within the last fourteen days, or if you take astemizole, droperidol, or terfenadine.

you are coping with a newly released cardiac arrest.
Contact a medical expert or doctor without delay if these connect with you.

Some health concerns may interact with Tofranil . Tell your medical professional or pharmacist if you have any medical conditions, particularly when any of the following affect you:

if you happen to be pregnant, likely to get pregnant, or are breast-feeding

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if you adopt any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you've got allergies to medicines, foods, or another substances

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if you drink alcohol-containing beverages daily or you might have a reputation alcohol abuse

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if you are taking thyroid medicine or you've a good overactive thyroid, glaucoma, heart problems, kidney or liver problems, diabetes, seizures, the blood disease porphyria, or difficulty urinating

if you've a good suicidal thoughts or behavior, bipolar disorder, or other mental disorders; you're undergoing electroshock therapy; or you're scheduled to get any surgery.

Some MEDICINES MAY INTERACT with Tofranil . Tell your doctor if you adopt every other medicines, especially any with the following:

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Azole antifungals (eg, fluconazole), cimetidine, duloxetine, flecainide, methylphenidate, mibefradil, phenothiazines (eg, chlorpromazine), propafenone, quinidine, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or terbinafine simply because they could raise the probability of Tofranil 's unwanted effects

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Arsenic, astemizole, droperidol, furazolidone, MAOIs (eg, phenelzine), pimozide, streptogramins (eg, dalfopristin), terfenadine, or tramadol since the probability of high blood pressure levels, serious cardiovascular disease (eg, irregular heartbeat), or seizures might be increased

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Barbiturates (eg, phenobarbital) or phenytoin because they may decrease Tofranil 's effectiveness

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Anticholinergics (eg, benztropine), carbamazepine, or sympathomimetics (eg, phenylephrine) as the probability of their unwanted effects could possibly be increased by Tofranil

Clonidine, guanethidine, or guanfacine his or her effectiveness might be decreased by Tofranil

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