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Micronase (Glyburide) is an oral diabetes medicine that assists control blood sugar.

Glyburide is used to take care of diabetes type 2 symptoms.

This drugs are not for treating type 1 diabetes.

Glyburide doubles for other purposes unlisted with this medication guide.


Take just as prescribed because of your doctor. Do not take in larger or smaller amounts and longer than recommended. Follow the directions on the prescription label. Your doctor may occasionally alter your dose to successfully obtain the best results.

Take glyburide using your first meal through the day, unless your physician notifys you otherwise.

Your blood sugar levels should be checked often, and you might need other blood tests at your doctor's office. Visit a medical expert regularly.
Know the signs and symptoms of low blood glucose (hypoglycemia) and the ways to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a method to obtain sugar obtainable in case you've symptoms of low blood glucose levels. Sugar sources include orange juice, glucose gel, candy, or milk. If you've severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can present you with a prescription for a glucagon emergency injection kit and inform you how you can provide injection.

Also watch out for warning signs of blood glucose levels which is too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dermititis, blurred vision, and weight-loss.

Check your blood glucose levels carefully during a time of stress or illness, should you travel, exercise more than usual, are drinking alcohol, or skip meals. These things can affect your glucose levels plus your dose needs could also change.

Your doctor might want one to stop taking glyburide for any small amount of time in case you become ill, have a very fever or infection, or if you might have surgical procedures or a medical emergency.
Ask your physician how you can adjust your glyburide dose as required. Do not improve your medication dose or schedule without a medical expert's advice.

If you'll find any alterations in the brand, strength, or type of glyburide you use, your dosage needs may change. Always check your refills to ensure that you have received the best logo and sort of medicine prescribed from your doctor.


Take as prescribed by your doctor.


Store at room temperature, shielded from moisture, heat, and light-weight.


Active ingredient: Glyburide

Side Effects

Stop using glyburide and obtain emergency medical help if you have these indications of an allergic reaction: hives; breathlessness; swelling of one's face, lips, tongue, or throat. Stop taking this medication and call your physician at once if you have any of these serious negative effects:

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the epidermis or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots through your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious unwanted effects can include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete list of unwanted effects and others may occur. Call your physician for medical advice about unwanted effects.


You should not use this medication in case you are allergic to glyburide, or:

in the event you are receiving care with bosentan (Tracleer);

if you might have type 1 diabetes; or

in case you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

To be sure to can safely take glyburide, tell your physician if you've all of these other conditions:

hemolytic anemia (an absence of red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

liver or kidney disease;

if you are allergic to sulfa drugs; or

if you've been using insulin or taking chlorpropamide (Diabinese).

Certain oral diabetes medications may enhance your probability of serious heart disease. However, not treating your diabetes can damage your heart and other organs. Talk to a medical expert regarding the risks and important things about handling your diabetes with glyburide.

FDA pregnancy category C. It is not known whether glyburide will harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication near the time of delivery. Tell your medical professional if you are pregnant or plan to conceive while using the this medication. It is not known whether glyburide passes into breast milk or if it might harm a nursing baby.

Do not use this medication without telling your doctor in the event you are breast-feeding an infant. Older adults could possibly be more likely to have low blood glucose levels while taking glyburide.


Important safety information:

You should avoid using prescription drugs in the event you are allergic to glyburide, in case you are being treated with bosentan (Tracleer), if you've got type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin).

Before taking glyburide, tell a medical expert in case you are allergic to sulfa drugs, if you've got been using insulin or chlorpropamide (Diabinese), or if you have hemolytic anemia (a lack of red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care not to let your blood glucose get too low. Low blood sugar (hypoglycemia) can take place in the event you skip a meal, exercise to much time, are drinking alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets along with you in case you've got low blood glucose. Other sugar sources include orange juice and milk. Be sure your loved ones and pals know the best way to assist you in a crisis.

Drug interactions

Tell a medical expert about all the other medications you utilize, especially:

a blood thinner like warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor like enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), yet others; or

an antibiotic like ciprofloxacin (Cipro), levofloxacin (Levaquin), while others.

Using certain medicines can make it harder for you to definitely tell when you have low blood sugar. Tell your physician if you use any of the following:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers for example atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), and others.

You might be more prone to have hyperglycemia (high blood glucose levels) in case you take glyburide with:


diuretics (water pills);

steroids (prednisone among others);

phenothiazines (Compazine among others);

thyroid medicine (Synthroid and others);

birth control pills and other hormones;

heart or blood pressure level medications (Cartia, Cardizem, Nifedical, Covera, Verelan, and others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);

seizure medicines (Dilantin among others); and

diet pills or medicines to deal with asthma, colds or allergies.

You could possibly be more prone to have hypoglycemia (low blood glucose) if you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or blood pressure level medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, and others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or other salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, yet others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists are certainly not complete and you'll find many other medicines that may increase or minimizing the effects of glyburide on cutting your blood glucose levels. Tell your medical professional about all medications you employ. This includes prescription, over-the-counter, vitamin, and herbal products. Do not find a new medication without telling your medical professional.


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