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Eldepryl is indicated as an adjunct within the management of Parkinsonian patients being treated with levodopa/carbidopa who exhibit deterioration inside the quality with their reaction to this therapy.


Take this medicine only as directed by your doctor. Do not take really it, don't take it often, and don't take it for a longer time than a medical expert ordered.

It is most beneficial to take this medicine before breakfast and without liquids.

If you are while using disintegrating tablet, ensure both hands are dry prior to deciding to handle the tablet. Do not open the blister pack made up of these days until you happen to be ready to get it. Remove these days from the blister pack by peeling back the foil, then taking named out. Do not push these days over the foil. Do not break or split the tablet. Place today for the top of your tongue, where it will melt quickly. Do not eat food or drink liquids for 5 minutes before or after taking this medicine.

If you miss a dose on this medicine, take it as quickly as possible. However, if it is almost time for your next dose, skip the missed dose and get back on your normal dosing schedule. Do not double doses.


The dose on this medicine vary for various patients. Follow a medical expert's orders or perhaps the directions for the label. The following information includes exactly the average doses of this medicine. If your dose is unique, tend not to put it back unless your physician notifys you to take action.

The amount of medicine that you simply take depends for the strength of the medicine. Also, the number of doses you're taking daily, time allowed between doses, along with the time period you take the medicine depend for the problem for which you are while using the medicine.
For oral dosage form (tablets):
For Parkinson's disease:


Store the medicine in the closed container at room temperature, far from heat, moisture, and direct light. Keep from freezing.
Keep from the reach of children.
Do not keep outdated medicine or medicine will no longer needed.


Eldepryl can be a levorotatory acetylenic derivative of phenethylamine. It is commonly referred to inside the clinical and pharmacological literature as l-deprenyl.

Side Effects

Along featuring its needed effects, medicine could cause some uncomfortable side effects. Although not these side effects may occur, if they occur they may need medical assistance.

Check with your medical professional immediately if these things side effects occur:

More common
Chest pain (severe)
enlarged pupils
fast or slow heartbeat
headache (severe)
increase in unusual movements with the body
increased sensitivity from the eyes to light
increased sweating (possibly with fever or cold, clammy skin)
mood or any other mental changes
nausea and vomiting (severe)
stiff or sore neck

Less common or rare
Bloody or black, tarry stools
convulsions (seizures)
decreased urine
difficult or frequent urination
difficulty with breathing
difficulty with speaking
difficulty with swallowing
dizziness or lightheadedness, particularly when arising from your lying or sitting position
dry mouth
hallucinations (seeing, hearing, or feeling stuff that usually are not there)
increased thirst
irregular heartbeat
large, flat, blue, or purplish patches inside skin
lip smacking or puckering
loss of appetite
loss of balance control
muscle pain or cramps
nausea or vomiting
numbness or tingling inside hands, feet, or lips
puffing in the cheeks
rapid or worm-like movements with the tongue
restlessness or wish to keep moving
severe stomach pain
shakiness in the legs, arms, hands, or feet
shortness of breath
swelling in the feet or lower legs
swelling or inflammation in the mouth
tightness inside the chest
trembling or shaking from the hands or feet
twisting movements with the body
uncontrolled chewing movements
uncontrolled movements with the face, neck, back, arms, or legs
unusual tiredness or weakness
vomiting of blood or material that looks like coffee grounds

Get emergency help immediately if the following signs and symptoms of overdose occur:

Symptoms of overdose
Agitation or irritability
chest pain
difficulty opening the mouth or lockjaw
dizziness (severe) or fainting
fast or irregular pulse (continuing)
high fever
high or low blood pressure levels
severe spasm the location where the head and heels are bent backward and the body arched forward
troubled breathing

Some unwanted effects may occur that always don't need medical attention. These unwanted side effects might have to go away during treatment since your body adjusts to the medicine. Also, your health care professional might be able to share with you solutions to prevent or reduce many of these unwanted side effects. Check along with your health care professional if these things unwanted side effects continue or are bothersome or if you might have any queries about them:

More common
Abdominal or stomach pain
dizziness or feeling faint
runny nose
stuffy nose
trouble with sleeping

Less common or rare
back or leg pain
blurred or double vision
body aches or pain
burning from the lips, mouth, or throat
dryness or soreness of the throat
frequent urge to urinate
inability to move
increased sweating
irritability (temporary)
memory problems
pounding or fast heartbeat
red, raised, or itchy skin
ringing or buzzing in the ears
slow or difficult urination
slowed movements
taste changes
uncontrolled closing of the eyelids
unusual a feeling of well-being
unusual weight loss
voice changes

Other negative effects not listed may also occur in some patients. If you notice any other effects, check with your doctor.


It is critical that your medical professional look at progress at regular visits to allow for changes in your dose and to check for any negative effects.

Do not take selegiline if you have used meperidine (e.g., Demerol®) or perhaps an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past 14 days. If you do, you could develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high body temperature, very high blood pressure, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you happen to be applying this medicine. Using these medicines together could cause uncomfortable side effects.

Selegiline may cause serious unwanted effects when used together with some antidepressants. Tell your doctor if you've used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past two weeks.

When selegiline is taken at doses of 10 mg or less each day for the treatments for Parkinson's disease, there won't be any restrictions on food or beverages consume or drink. However, the opportunity exists that dangerous reactions, for example sudden high blood pressure, may occur if doses above those used by Parkinson's disease are taken with certain foods, beverages, or other medicines. These foods, beverages, and medicines include:

Also, for about 14 days as soon as you stop using this medicine, these foods, beverages, along with other medicines may continue to react with selegiline whether or not this was taken in doses greater than those usually useful for Parkinson's disease.

Check with your physician or hospital emergency room immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you might be taking this medicine. These may be signs of a serious complication that will possess a doctor's attention.

Dizziness, lightheadedness, or fainting may occur, particularly when you receive up from the lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, check with your physician.

Selegiline could cause dryness from the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice inside your mouth, or make use of a saliva substitute. However, should your mouth continues to feel dry in excess of 14 days, check along with your medical doctor or dentist. Continuing dryness in the mouth may increase the chance of dental disease, including cavities, gum disease, and fungus infections.

It is essential that your physician look at your skin for melanoma (tumor) regularly if you've got Parkinson's disease.

Do not stop using this medicine without first checking with your physician. Your doctor may want that you reduce gradually the amount you are taking before stopping completely.

Hallucinations may appear in some patients. This is more established with elderly patients. If you might have hallucinations, consult a medical expert.

Some individuals who have used this medicine had unusual changes in their behavior. Talk with a medical expert in the event you start having problems with gambling or increased libido while using this medicine.

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